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线性分子式:
HOCH2CH2NHNH2
化学文摘社编号:
分子量:
76.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-711-6
Beilstein/REAXYS Number:
1731669
MDL number:
Assay:
≥95% (GC)
InChI key
GBHCABUWWQUMAJ-UHFFFAOYSA-N
InChI
1S/C2H8N2O/c3-4-1-2-5/h4-5H,1-3H2
SMILES string
NNCCO
assay
≥95% (GC)
Quality Level
refractive index
n20/D 1.493
bp
155-160 °C/32 mmHg (lit.)
mp
−70 °C (lit.)
density
1.123 g/mL at 25 °C (lit.)
functional group
amine, hydrazine, hydroxyl
General description
2-羟基乙基肼可与具有强吸电子取代基的β-二酮反应生成5-羟基-4,5-二氢吡唑。
Other Notes
可能实行销售限制
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
170.6 °F - closed cup
flash_point_c
77 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
A new method for the synthesis of 1, 4, 5-oxadiazocines and its application in the structure modification of natural products.
Liu W, et al.
Tetrahedron Letters, 46(46), 8009-8012 (2005)
Solvent-free synthesis of 3, 5-di-tert-butylpyrazole and 3, 5-di-substituted-butylpyrazol-1-ylethanol.
Van Wyk JL, et al.
J. Chem. Res. (M), 26(8), 474-477 (2012)
Smaail Radi et al.
Molecules (Basel, Switzerland), 21(8), doi:10-doi:10 (2016-08-17)
A pyridylpyrazole bearing a hydroxyethyl substituent group has been synthesized by condensation of (Z)-4-hydroxy-4-(pyridin-2-yl)but-3-en-2-one with 2-hydroxyethylhydrazine. The compound was well characterized and its structure confirmed by single crystal X-ray diffraction. Density functional calculations have been performed using DFT method with
Reaction of 2-hydroxyethylhydrazine with a trifluoromethyl-?-diketone: Study and structural characterization of a new 5-hydroxy-5-trifluoromethyl-4, 5-dihydropyrazole intermediate.
Montoya V, et al.
Journal of Fluorine Chemistry, 128(9), 1007-1011 (2007)
C M Czarnecki
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 91(2), 607-611 (1988-01-01)
1. Toxicity of 2-hydrazinoethanol was investigated in turkey poults 2-6 weeks posthatch. 2. Significant depression of body wt was evident at concentrations of the drug as low as 10 ppm. 3. Severe anorexia closely paralleled a highly significant decrease in
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