Merck
CN

560006

Sigma-Aldrich

4-羟基-5-甲基-3(2H)-呋喃酮

97%

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线性分子式:
C4OH2OCH3OH
CAS号:
分子量:
114.10
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

97%

mp

129-133 °C (lit.)

SMILES string

CC1=C(O)C(=O)CO1

InChI

1S/C5H6O3/c1-3-5(7)4(6)2-8-3/h7H,2H2,1H3

InChI key

DLVYTANECMRFGX-UHFFFAOYSA-N

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应用

4-Hydroxy-5-methyl-3-furanone may be used in oxidoreductase assay for the evaluation of oxidoreductase activity.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Highly effective inhibition of biofilm formation by the first metagenome-derived AI-2 quenching enzyme.
Weiland-Brauer N, et al.
Frontiers in Microbiology, 7 (2016)
An efficient flow-photochemical synthesis of 5H-furanones leads to an understanding of torquoselectivity in cyclobutenone rearrangements.
David C Harrowven et al.
Angewandte Chemie (International ed. in English), 51(18), 4405-4408 (2012-03-24)
Klaus Winzer et al.
Microbiology (Reading, England), 148(Pt 4), 909-922 (2002-04-05)
Many bacteria produce extracellular molecules which function in cell-to-cell communication. One of these molecules, autoinducer 2 (AI-2), was first described as an extracellular signal produced by Vibrio harveyi to control luciferase expression. Subsequently, a number of bacteria have been shown
Doris Marko et al.
Chemical research in toxicology, 16(1), 48-55 (2003-04-16)
We investigated the effect of a series of Maillard reaction products formed from carbohydrates under household heating conditions on the growth of human tumor cells in vitro. 4-Hydroxy-5-methyl-3-(2H)-furanone (1) was found to potently enhance the proliferation of human tumor cells.
F B Whitfield et al.
Journal of agricultural and food chemistry, 49(2), 816-822 (2001-03-23)
The reaction of 4-hydroxy-5-methyl-3(2H)-furanone (HMF) with cysteine or hydrogen sulfide at pH 6.5 for 60 min at 140 degrees C produced complex mixtures of volatile compounds, the majority of these containing either sulfur or nitrogen. Of the 68 compounds detected

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