产品名称
3-氯-6-甲基哒嗪, 97%
InChI
1S/C5H5ClN2/c1-4-2-3-5(6)8-7-4/h2-3H,1H3
SMILES string
Cc1ccc(Cl)nn1
InChI key
PRORLQAJNJMGAR-UHFFFAOYSA-N
assay
97%
form
solid
mp
58-62 °C
functional group
chloro
Quality Level
Application
3-Chloro-6-methyl pyridazine can undergo nickel catalyzed cross coupling reaction with aromatic and heteroaromatic halides, to give the corresponding substituted aryl- and heteroaryl pyridazines. It can also be used in the synthesis of a p38MAP kinase inhibitor with therapeutic potential in the treatment of autoimmune and inflammatory diseases.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Sengmany S, et al.
The Journal of Organic Chemistry, 72(15), 5631-5636 (2007)
"Development of a Practical and Scalable Synthesis of a Potent p38 Mitogen-Activated Protein Kinase Inhibitor"
Yoshida S, et al.
The Journal of Organic Chemistry, 16(11), 1818-1826 (2012)
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