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855286

5-氨基尿嘧啶

Name: 5-氨基尿嘧啶
Brand: ALDRICH

98%

别名:

5-氨基-2,4-二羟基嘧啶, 5-氨基-2,4-嘧啶二醇

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关于此项目

经验公式（希尔记法）:

C₄H₅N₃O₂

化学文摘社编号:

932-52-5

分子量:

127.10

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24888374

EC Number:

213-252-3

Beilstein/REAXYS Number:

127250

MDL number:

MFCD00006025

Assay:

98%

Form:

powder

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属性

Quality Level

200

assay

98%

form

powder

mp

>300 °C (lit.)

SMILES string

NC1=CNC(=O)NC1=O

InChI

1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)

InChI key

BISHACNKZIBDFM-UHFFFAOYSA-N

说明

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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5-(N-Trifluoromethylcarboxy)aminouracil as a Potential DNA Radiosensitizer and Its Radiochemical Conversion into N-Uracil-5-yloxamic Acid.

Paulina Spisz et al.

International journal of molecular sciences, 21(17) (2020-09-05)

Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that

Cytological demonstration of DNA synthesis inhibition at late S by 5-amino-uracil.

F Cortés et al.

Experimental cell research, 148(2), 503-507 (1983-10-15)

Meristematic cells of Allium cepa were treated with 5-amino-uracil (5-AU) while incorporating 5-bromodeoxyuridine (BrdU) into DNA until complete inhibition of mitosis was obtained. The pattern of BrdU substitution in interphase nuclei detected by FPG technique in the cells so treated

Reproductive death of Chinese hamster V79 cells after exposure to chemical inhibitors of DNA synthesis.

D Suciu

The International journal of biochemistry, 23(11), 1245-1249 (1991-01-01)

1. The results of this study have contributed to the definition of three categories of chemical inhibitors of DNA replication in mammalian cells. 2. Inhibitors of replicon cluster initiation [4-nitroquinoline-N-oxide (4-NQO), etoposide (VP-16), teniposide (VM-26), amsacrine (m-AMSA), N-methyl-N'-nitro-N-nitrozoguanidine (MNNG), cis-Pt(II)diammine

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全球贸易项目编号

货号	GTIN
855286-25G	04061833024720