Merck
CN
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文件

D48400

Sigma-Aldrich

:2,6-二叔丁基苯酚

99%

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线性分子式:
[(CH3)3C]2C6H3OH
CAS号:
128-39-2
分子量:
206.32
Beilstein:
1841887
EC 号:
204-884-0
MDL编号:
MFCD00008820
PubChem化学物质编号:
24893900
NACRES:
NA.22

蒸汽压

<0.01 mmHg ( 20 °C)

检测方案

99%

形式

crystals

bp

253 °C (lit.)

mp

34-37 °C (lit.)

SMILES string

CC(C)(C)c1cccc(c1O)C(C)(C)C

InChI

1S/C14H22O/c1-13(2,3)10-8-7-9-11(12(10)15)14(4,5)6/h7-9,15H,1-6H3

InChI key

DKCPKDPYUFEZCP-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554)

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象形图

Exclamation markEnvironment
GHS07,GHS09

警示用语：

Warning

危险声明

H315 - H410

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

227.3 °F - closed cup

闪点(°C)

108.5 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Anouar Hafiane et al.
The Canadian journal of cardiology, 35(6), 770-781 (2019-06-04)
Small peptides based on the C-terminal domain of apo E have recently been proposed as ATP-binding cassette transporter A1 (ABCA1) agonist with therapeutic potential. Previous work has shown that a novel synthetic peptide, CS-6253, acts synergistically with apolipoprotein A-I or
Caitlin E Cornell et al.
Biophysical journal, 113(6), 1200-1211 (2017-08-13)
A persistent challenge in membrane biophysics has been to quantitatively predict how membrane physical properties change upon addition of new amphiphiles (e.g., lipids, alcohols, peptides, or proteins) in order to assess whether the changes are large enough to plausibly result
J B Kramer et al.
Bioorganic & medicinal chemistry, 3(4), 403-410 (1995-04-01)
The preparation of hydroxylamine analogs of 2,6-di-tert-butylphenols (DTBP) and the inhibition of cyclooxygenase (CO) and 5-lipoxygenase (5-LO) by these compounds is discussed.
George N Ziakas et al.
Bioorganic & medicinal chemistry, 14(16), 5616-5624 (2006-05-13)
Amine or amide derivatives bearing the 2,6-di-tert-butyl phenol moiety are synthesised. Almost all are antioxidants, reduce acute inflammation and inhibit COX-1 and lipoxygenase activity. The most potent anti-inflammatory, COX-1 inhibitor and antioxidant agent, with low toxicity, is 2,6-di-tert-butyl-4-thiomorpholin-4-ylmethyl-phenol.
Daniel B Williams et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(17), 7417-7424 (2002-08-28)
The GABA(A) receptor is a target of many general anesthetics, such as propofol. General anesthetic binding sites are distinct from the GABA binding sites. At low concentrations, the anesthetics potentiate the currents induced by submaximal GABA concentrations. At higher concentrations
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