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Merck
CN

D67200

2,3-二氯-1,4-萘醌

98%

别名:

二氯萘醌

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关于此项目

经验公式(希尔记法):
C10H4Cl2O2
化学文摘社编号:
分子量:
227.04
Beilstein:
1073511
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

98%

表单

powder

mp

194-197 °C (lit.)

SMILES字符串

ClC1=C(Cl)C(=O)c2ccccc2C1=O

InChI

1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

InChI key

SVPKNMBRVBMTLB-UHFFFAOYSA-N

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象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

农药列管产品
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C A Pritsos et al.
Biochemical pharmacology, 35(7), 1131-1135 (1986-04-01)
Dietary exposure of rats to a high concentration of 2,3-dichloro-1,4-naphthoquinone (CNQ) (2 g/kg diet) for 60 days altered cardiac mitochondrial function and activities of anti-oxidant enzymes in hepatic and cardiac tissue. CNQ moderately depressed the cardiac mitochondrial respiratory control ratio
Ibrahim A Darwish
Journal of AOAC International, 88(1), 38-45 (2005-03-12)
Three simple and sensitive spectrophotometric methods were developed and validated for determination of the hydrochloride salts of fluoxetine, sertraline, and paroxetine in their pharmaceutical dosage forms. These methods were based on the reaction of the N-alkylvinylamine formed from the interaction
C A Pritsos et al.
Biochemical pharmacology, 33(23), 3771-3777 (1984-12-01)
The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to substrate-depleted, GSH-supplemented rat liver mitochondria resulted in a dose-dependent depletion of reactable suflhydryl groups and a concomitant increase in mitochondrial disulfide content at a ratio of 2 thiols depleted/disulfide generated. The molar ratio of
Involvement of superoxide in the interaction of 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes.
C A Pritsos et al.
Archives of biochemistry and biophysics, 217(1), 98-109 (1982-08-01)
Christophe Morisseau et al.
Environmental health perspectives, 117(12), 1867-1872 (2010-01-06)
Legislation at state, federal, and international levels is requiring rapid evaluation of the toxicity of numerous chemicals. Whole-animal toxicologic studies cannot yield the necessary throughput in a cost-effective fashion, leading to a critical need for a faster and more cost-effective

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