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D67200

2,3-二氯-1,4-萘醌

Name: 2,3-二氯-1,4-萘醌
Brand: ALDRICH

98%

别名:

二氯萘醌

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关于此项目

经验公式（希尔记法）:

C₁₀H₄Cl₂O₂

化学文摘社编号:

117-80-6

分子量:

227.04

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24894043

EC Number:

204-210-5

Beilstein/REAXYS Number:

1073511

MDL number:

MFCD00001677

Assay:

98%

Form:

powder

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属性

assay

98%

form

powder

mp

194-197 °C (lit.)

SMILES string

ClC1=C(Cl)C(=O)c2ccccc2C1=O

InChI

1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

InChI key

SVPKNMBRVBMTLB-UHFFFAOYSA-N

说明

pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301,H315,H319,H410

pcodes

P264 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

农药列管产品

危险化学品

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A redox cycling mechanism of action for 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes and the role of sulfhydryl groups.

C A Pritsos et al.

Biochemical pharmacology, 33(23), 3771-3777 (1984-12-01)

The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to substrate-depleted, GSH-supplemented rat liver mitochondria resulted in a dose-dependent depletion of reactable suflhydryl groups and a concomitant increase in mitochondrial disulfide content at a ratio of 2 thiols depleted/disulfide generated. The molar ratio of

Metabolic consequences of dietary 2,3-dichloro-1,4-naphthoquinone (CNQ) in the rat. Alteration in anti-oxidant enzyme activities.

C A Pritsos et al.

Biochemical pharmacology, 35(7), 1131-1135 (1986-04-01)

Dietary exposure of rats to a high concentration of 2,3-dichloro-1,4-naphthoquinone (CNQ) (2 g/kg diet) for 60 days altered cardiac mitochondrial function and activities of anti-oxidant enzymes in hepatic and cardiac tissue. CNQ moderately depressed the cardiac mitochondrial respiratory control ratio

Development and validation of spectrophotometric methods for determination of fluoxetine, sertraline, and paroxetine in pharmaceutical dosage forms.

Ibrahim A Darwish

Journal of AOAC International, 88(1), 38-45 (2005-03-12)

Three simple and sensitive spectrophotometric methods were developed and validated for determination of the hydrochloride salts of fluoxetine, sertraline, and paroxetine in their pharmaceutical dosage forms. These methods were based on the reaction of the N-alkylvinylamine formed from the interaction

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全球贸易项目编号

货号	GTIN
D67200-100G	04061833587850
D67200-5G	04061831826593