H6377
2-巯基吡啶-N-氧化物 锌盐
≥95%
别名:
Mercaptopyridine N-oxide 锌盐, 羟基吡啶硫酮
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关于此项目
经验公式（希尔记法）:
C10H8N2O2S2Zn
化学文摘社编号:
分子量:
317.70
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
236-671-3
MDL number:
Assay:
≥95%
InChI key
OTPSWLRZXRHDNX-UHFFFAOYSA-L
InChI
1S/2C5H5NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4,8H;/q;;+2/p-2
SMILES string
O1N2C=CC=CC2=[S][Zn]13ON4C=CC=CC4=[S]3
assay
≥95%
Quality Level
Application
- 抗菌纳米涂层：对化合物1-羟基吡啶-2-硫酮锌盐在抗菌纳米涂层中的功效进行了评估，显示了其在提高医疗保健和工业环境中用于防止微生物污染的此类涂层的性能方面的作用（Molling et al., 2014）。
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - STOT RE 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Viswanath Kasi et al.
Biochemical and biophysical research communications, 410(2), 270-275 (2011-06-10)
Zinc pyrithione (ZPT), has a strong anti-apoptotic effect when administered just before reperfusion. Because oxidative stress has been proposed to contribute to myocardial reperfusion injury, we tested whether ZPT can reduce the production of reactive oxygen species during reoxygenation in
Kathy Kerr et al.
International journal of dermatology, 50(1), 102-113 (2010-12-25)
Dandruff is a common scalp condition characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect underlying histopathologic and biochemical events that must be reversed if treatment is to be effective. This study aimed to better characterize the state
Emil Rudolf et al.
Toxicology letters, 204(2-3), 164-173 (2011-05-12)
Zinc pyrithione is used as a topical agent in a range of medicinal and cosmetic applications. Despite its extensive use and reported beneficial effects in treatment of various dermal problems, its potential toxicity towards skin cells remains relatively underexplored. In
N L Reeder et al.
The British journal of dermatology, 165 Suppl 2, 9-12 (2011-09-23)
Zinc pyrithione (ZPT) is the active ingredient most commonly used in many antidandruff treatments. Despite decades of successful use to treat human scalps, little is understood about the antifungal mechanism of action of ZPT. The objective of this study is
Nancy L Reeder et al.
Antimicrobial agents and chemotherapy, 55(12), 5753-5760 (2011-09-29)
Zinc pyrithione (ZPT) is an antimicrobial material with widespread use in antidandruff shampoos and antifouling paints. Despite decades of commercial use, there is little understanding of its antimicrobial mechanism of action. We used a combination of genome-wide approaches (yeast deletion
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