assay
99%
mp
211-213 °C (lit.)
SMILES string
OC(=O)c1ccc2[nH]ccc2c1
InChI
1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12)
InChI key
IENZCGNHSIMFJE-UHFFFAOYSA-N
General description
Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by 1H NMR and various one- and two-dimensional NMR techniques have been reported.
Application
Indole-5-carboxylic acid is the suitable reagent used to study the intramolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films.
- Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
- Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
- Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
- Reactant for synthesis of indirubin derivatives
- Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
- Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Characterization of the unsymmetrical trimer of indole-5-carboxylic acid by proton NMR spectroscopy.
Mackintosh JG, et al.
Magnetic Resonance in Chemistry, 32(9), 559-561 (1994)
Inhibitive action of indole-5-carboxylic acid towards corrosion of mild steel in deaerated 0.5 M sulfuric acid solutions.
Quartarone G, et al.
Applied Surface Science, 252(23), 8251-8257 (2006)
Electropolymerisation of indole-5-carboxylic acid.
GordonaMackintosh J and Andrew R.
J. Chem. Soc., Faraday, 90(8), 1121-1125 (1994)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I5400-1G | 04061833857328 |
| I5400-5G | 04061833857335 |