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Merck
CN

M1626

6-甲氧基哈马兰

crystalline

别名:

4,9-二氢-6-甲氧基-1-甲基-3H-吡啶并(3,4-b)吲哚

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关于此项目

经验公式（希尔记法）:
C13H14N2O
化学文摘社编号:
3589-73-9
分子量:
214.26
NACRES:
NA.22
PubChem Substance ID:
57654356
UNSPSC Code:
12352100
MDL number:
MFCD00055938

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产品名称

6-甲氧基哈马兰, crystalline

InChI

1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3

SMILES string

COc1ccc2[nH]c3C(C)=NCCc3c2c1

InChI key

HMBHRMFLDKKSCT-UHFFFAOYSA-N

form

crystalline

color

yellow

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM4(1132), CHRM5(1133), DRD1(1812), DRD5(1816), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR2C(3358), HTR3A(3359), HTR5A(3361), HTR6(3362), HTR7(3363), LOC730413(730413), SLC6A2(6530), SLC6A4(6532)
rat ... Drd2(24318), Drd3(29238), Drd4(25432), Htr2a(29595)

相关类别

Biochem/physiol Actions

弱血清素抑制剂

Application

  • Reactant for preparation of TRPV1-dependent vasodilator

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
108F0464

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Fernando D Villarruel et al.
Physical chemistry chemical physics : PCCP, 22(36), 20901-20913 (2020-09-12)
3,4-Dihydro-β-carbolines (DHβCs) are a set of endogenously synthesized alkaloids spread over a great variety of living species (e.g., plants, animals and microorganisms), playing a broad spectrum of biological, biochemical and/or pharmacological roles, in a structure-dependent manner. Addressing unresolved fundamental aspects
V P Poshivalov
Biulleten' eksperimental'noi biologii i meditsiny, 99(3), 323-325 (1985-03-01)
The ethological spectrum of four beta-carbolines was studied for intraspecific aggression, sociability integration and individual behavior. It was established that beta-carboline-3-carboxyethyl ether given at subconvulsant doses increases aggression, lowers sociability as a diazepam antagonist. Diazepam reduces aggression and increases sociability.
M Micaela Gonzalez et al.
International journal of antimicrobial agents, 52(4), 459-468 (2018-07-15)
Several commercial and novel synthetic β-carbolines (βCs) were evaluated for their antiviral activity against herpes simplex virus type 1 (HSV-1) using an adapted MTS assay. Of 21 drugs tested, although 11 exerted antiviral activity at non-cytotoxic concentrations, only 3 of
Sudeep Karki et al.
Analytical biochemistry, 587, 113463-113463 (2019-10-02)
Synaptic adhesion molecules, including presynaptic neurexins (NRXNs) and post-synaptic leucine-rich repeat transmembrane (LRRTM) proteins are important for development and maintenance of brain neuronal networks. NRXNs are probably the best characterized synaptic adhesion molecules, and one of the major presynaptic organizer

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