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Merck
CN

M1641

甲氧那明 盐酸盐

≥99%

别名:

2-甲氧基-N,α-二甲基苯乙胺 盐酸盐, NSC 65644

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关于此项目

经验公式(希尔记法):
C11H17NO · HCl
化学文摘社编号:
分子量:
215.72
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
226-993-2
MDL number:
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产品名称

甲氧那明 盐酸盐, ≥99%

InChI key

FGSJNNQVSUVTPW-UHFFFAOYSA-N

InChI

1S/C11H17NO.ClH/c1-9(12-2)8-10-6-4-5-7-11(10)13-3;/h4-7,9,12H,8H2,1-3H3;1H

SMILES string

Cl.CNC(C)Cc1ccccc1OC

assay

≥99%

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

Quality Level

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R T Coutts et al.
Drug metabolism and disposition: the biological fate of chemicals, 22(5), 756-760 (1994-09-01)
Metabolism of methoxyphenamine (MP) was conducted in vitro using commercially available microsomes prepared from human AHH-1 TK+/-cells in which CYP2D6 had been expressed. This study has confirmed the involvement of CYP2D6 in the metabolism of MP to O-desmethylmethoxyphenamine (ODMP) and
Weili Wei et al.
Respirology (Carlton, Vic.), 15(5), 830-836 (2010-06-16)
Sequential three-step empirical therapy is useful for the management of chronic cough. The purpose of this study was to evaluate the efficacy and safety of modified sequential three-step empirical therapy. Consecutive patients (n = 240) with chronic cough were recruited
W A Lau et al.
British journal of pharmacology, 101(2), 394-398 (1990-10-01)
1. Nasal resistance in anaesthetized rats was assessed by measuring air overflow during ventilation of the nasal passages at constant pressure. Nasal basal resistance was reduced in a dose-dependent manner by methoxyphenamine hydrochloride (0.01-30 mg kg-1, i.v.), pseudoephedrine hydrochloride (0.03-3
Mario Thevis et al.
European journal of mass spectrometry (Chichester, England), 14(3), 145-152 (2008-08-19)
Methoxyphenamine (o-methoxy-N,alpha-dimethylphenethylamine, Orthoxine) used in earlier times as a bronchodilator is prohibited in sports according to the regulations of the World Anti-Doping Agency (WADA). The drug and several of its metabolites are commonly analysed in doping control screening assays using
A Guttman
Electrophoresis, 16(10), 1900-1905 (1995-10-01)
A systematic approach is described for methods development of chiral separations of weak acidic and basic compounds by capillary electrophoresis, using several natural and derivatized neutral cyclodextrins as chiral selectors. Following the methods development scheme suggested here, the appropriate pH

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