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文件

M47604

3-甲基戊烯二酸

Name: 3-甲基戊烯二酸
Brand: ALDRICH

99%

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别名:

β-Methylglutaric acid, 3-Methylpentanedioic acid

线性分子式:

CH₃CH(CH₂COOH)₂

CAS号:

626-51-7

分子量:

146.14

Beilstein:

1759502

EC 号:

210-951-5

MDL编号:

MFCD00002727

PubChem化学物质编号:

24896942

NACRES:

NA.22

检测方案

99%

mp

81-86 °C (lit.)

SMILES string

CC(CC(O)=O)CC(O)=O

InChI

1S/C6H10O4/c1-4(2-5(7)8)3-6(9)10/h4H,2-3H2,1H3,(H,7,8)(H,9,10)

InChI key

XJMMNTGIMDZPMU-UHFFFAOYSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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T1503

货号

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Episodes of severe metabolic acidosis in a patient with 3-methylglutaconic aciduria.

E A Haan et al.

European journal of pediatrics, 146(5), 484-488 (1987-09-01)

Persistent excretion of 3-methylglutaconic acid was found in a 6-month-old infant with multiple minor physical malformations and delayed development. During two episodes of intercurrent viral illness, the patient developed severe metabolic acidosis and excreted large amounts of lactate, 3-hydroxybutyrate and

X-linked dilated cardiomyopathy with neutropenia, growth retardation, and 3-methylglutaconic aciduria.

R I Kelley et al.

The Journal of pediatrics, 119(5), 738-747 (1991-11-01)

Seven boys with an apparently X-linked syndrome of dilated cardiomyopathy, growth retardation, neutropenia, and persistently elevated urinary levels of 3-methylglutaconate, 3-methylglutarate, and 2-ethylhydracrylate were studied. The natural history of the disorder was characterized by severe or lethal cardiac disease and

3-Methylglutaconic aciduria: a marker for as yet unspecified disorders and the relevance of prenatal diagnosis in a 'new' type ('type 4').

D Chitayat et al.

Journal of inherited metabolic disease, 15(2), 204-212 (1992-01-01)

The Mendelian disorder known as 3-methylgutaconic aciduria (McKusick 250950) gives evidence of allelic and locus heterogeneity. Type 1 has a mild clinical phenotype and confirmed 3-methylgutaconyl-CoA hydratase deficiency; inheritance is autosomal recessive. Other forms have major clinical manifestations and subdivide

Inherited 3-methylglutaconic aciduria in two brothers--another defect of leucine metabolism.

M Duran et al.

The Journal of pediatrics, 101(4), 551-554 (1982-10-01)

Two brothers, aged 7 and 5 years, who excreted large amounts of the leucine metabolites 3-methylglutaconic acid, 3-methylglutaric acid, and 3-hydroxyisovaleric acid, are described. The excretion of these metabolites could be enhanced by increasing the leucine intake. Restriction of the

3-Methylglutaconic aciduria in two infants.

B Hagberg et al.

Clinica chimica acta; international journal of clinical chemistry, 134(1-2), 59-67 (1983-10-31)

We studied two children who developed normally for the first 3-4 months of life and then displayed a failure-to-thrive syndrome, regression in psychomotor development, pronounced muscular hypotonia, and liver damage. At the age of about 1-2 years, optic atrophy and

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