M81101
琥珀酸单甲酯
95%
别名:
丁二酸一甲酯, 丁二酸单甲酯
质量水平
方案
95%
表单
powder
沸点
151 °C/20 mmHg (lit.)
mp
54-57 °C (lit.)
SMILES字符串
COC(=O)CCC(O)=O
InChI
1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
InChI key
JDRMYOQETPMYQX-UHFFFAOYSA-N
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Emma Heart et al.
The Biochemical journal, 403(1), 197-205 (2006-12-22)
The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences. Glycolysis and mitochondrial metabolism both have key
L Ladrière et al.
Annals of nutrition & metabolism, 41(2), 118-125 (1997-01-01)
Rats were fasted for 48 h, but infused with either NaCl or the sodium salt of monoethyl succinic acid (EMS), both delivered at a rate of 80 mumol/g body weight per day. The infusion of EMS, as compared to NaCl
Y P Zhou et al.
The American journal of physiology, 270(6 Pt 1), E988-E994 (1996-06-01)
Fasting inhibits glucose-induced insulin secretion. We investigated the role of a glucose fatty acid cycle for such inhibition and its molecular basis in pancreatic islets from 48-h fasted rats. The fasting-impaired insulin response to 27 mM glucose was restored by
Zrinka Rajić et al.
Molecules (Basel, Switzerland), 23(7) (2018-07-18)
Novel primaquine (PQ) and halogenaniline asymmetric fumardiamides 4a⁻f, potential Michael acceptors, and their reduced analogues succindiamides 5a⁻f were prepared by simple three-step reactions: coupling reaction between PQ and mono-ethyl fumarate (1a) or mono-methyl succinate (1b), hydrolysis of PQ-dicarboxylic acid mono-ester
S A Hinke et al.
British journal of pharmacology, 150(8), 1031-1043 (2007-03-07)
Two mechanisms have been proposed to explain the insulin-sensitising properties of metformin in peripheral tissues: (a) inhibition of electron transport chain complex I, and (b) activation of the AMP activated protein kinase (AMPK). However the relationship between these mechanisms and
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