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文件

M81101

Sigma-Aldrich

琥珀酸单甲酯

95%

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别名:
丁二酸一甲酯, 丁二酸单甲酯
线性分子式:
CH3OCOCH2CH2COOH
CAS号:
3878-55-5
分子量:
132.11
Beilstein:
1722669
EC 号:
223-408-2
MDL编号:
MFCD00002788
PubChem化学物质编号:
24897222
NACRES:
NA.22

检测方案

95%

形式

powder

bp

151 °C/20 mmHg (lit.)

mp

54-57 °C (lit.)

SMILES string

COC(=O)CCC(O)=O

InChI

1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)

InChI key

JDRMYOQETPMYQX-UHFFFAOYSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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D L Eizirik et al.
Molecular and cellular endocrinology, 118(1-2), 71-83 (1996-04-19)
Nitric oxide (NO) has been proposed as a possible mediator of beta-cell damage in human IDDM. This hypothesis is based on in vitro studies with rodent pancreatic islets. In the present study we examined whether human beta-cells are affected by
Isabelle Briaud et al.
Diabetes, 51(3), 662-668 (2002-03-02)
Chronic elevations in plasma levels of fatty acids (FAs) adversely affect pancreatic beta-cell function in type 2 diabetes. In vitro, we have previously shown that deleterious effects of prolonged exposure of isolated islets to FAs were dependent on the presence
L Ladrière et al.
General pharmacology, 31(3), 377-383 (1998-08-14)
1. Selected esters of succinic acid are currently under investigation as potential insulinotropic tools in the treatment of non-insulin-dependent diabetes. At variance with the methyl esters of succinic acid used in most of the work so far conducted from this
C J Reid et al.
Microbiology (Reading, England), 142 ( Pt 9), 2603-2612 (1996-09-01)
Amino acid uptake by the general amino acid permease (Aap) of Rhizobium leguminosarum strain 3841 was severely reduced by the presence of aspartate in the growth medium when glucose was the carbon source. The reduction in transport by the Aap
P Maechler et al.
The Journal of biological chemistry, 274(39), 27905-27913 (1999-09-17)
The effects of a transient exposure to hydrogen peroxide (10 min at 200 microM H(2)O(2)) on pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat islets, insulin secretion evoked by glucose (16.7 mM) or by the
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