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Merck
CN

M90003

反,反-粘康酸

95%

别名:

反,反-1,3-丁二烯-1,4-二羧酸, 反,反-2,4-己二烯二酸

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关于此项目

线性分子式:
HO2CCH=CHCH=CHCO2H
化学文摘社编号:
分子量:
142.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
222-724-8
Beilstein/REAXYS Number:
1722248
MDL number:
Assay:
95%
Form:
powder
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Quality Level

assay

95%

form

powder

bp

320 °C (lit.)

mp

290 °C (dec.) (lit.)

SMILES string

OC(=O)\C=C\C=C\C(O)=O

InChI

1S/C6H6O4/c7-5(8)3-1-2-4-6(9)10/h1-4H,(H,7,8)(H,9,10)/b3-1+,4-2+

InChI key

TXXHDPDFNKHHGW-ZPUQHVIOSA-N

General description

反,反-粘康酸是多不饱和二羧酸,特有共轭双键和反应性二羧基。主要用作聚酰胺和聚酯类合成单体的重要前体。

Application

反,反-粘康酸可用于:
  • 作为反应剂经由Diels-Alder环加成反应合成芳香单体。
  • 作为苯暴露的生物标记。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Bartczak et al.
Journal of toxicology and environmental health, 42(3), 245-258 (1994-07-01)
Muconic acid (MA) is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in humans exposed to levels as low as 1 ppm. We have modified a high-pressure liquid chromatography (HPLC) based assay
Sirirat Chanvaivit et al.
Mutation research, 626(1-2), 79-87 (2006-11-11)
Exposure to benzene can cause DNA damage and the subsequent development of cancer. In this study, study subjects were 31 laboratory workers at a petrochemical factory and 31 gasoline service attendants. Control subjects were 34 workers from a mail sorting
Francesco Marchetti et al.
Environmental health perspectives, 120(2), 229-234 (2011-11-17)
Benzene is an industrial chemical that causes blood disorders, including acute myeloid leukemia. We previously reported that occupational exposures near the U.S. Occupational Safety and Health Administration permissible exposure limit (8 hr) of 1 ppm was associated with sperm aneuploidy.



全球贸易项目编号

货号GTIN
M90003-1G04061834063773
M90003-10G04061835048694