InChI key
SOGBOGBTIKMGFS-UHFFFAOYSA-N
InChI
1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)
SMILES string
NNC(=O)c1cccs1
assay
≥98%
form
powder
mp
136-139 °C (lit.)
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Gyeong-Yi Kang et al.
Frontiers in cellular and infection microbiology, 10, 226-226 (2020-06-06)
Using a novel tissue-clearing method, we aimed to visualize the three-dimensional (3D) distribution of immune cells within Mycobacterium tuberculosis (Mtb)-infected mice lungs. Ethyl cinnamate-based tissue clearing of Mtb-infected mice lungs was performed to obtain transparent lung samples, which were then
Jaehun Park et al.
Virulence, 11(1), 430-445 (2020-05-15)
Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection. To address this controversy, the function
Sherry L Kurtz et al.
mSphere, 5(2) (2020-04-17)
Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people. Previous studies indicated that
M D Yates et al.
Tubercle, 65(4), 295-299 (1984-12-01)
Thiophen-2-carboxylic acid hydrazide (TCH) is used to distinguish TCH-sensitive bovine, 'Asian human' and 'African' strains from TCH-resistant 'classical' human strains of Mycobacterium tuberculosis. It has been claimed that this test cannot be applied to isoniazid-resistant strains as these also become
J I Moliva et al.
Mucosal immunology, 11(3), 968-978 (2017-09-21)
Current tuberculosis (TB) treatments include chemotherapy and preventative vaccination with Mycobacterium bovis Bacillus Calmette-Guérin (BCG). In humans, however, BCG vaccination fails to fully protect against pulmonary TB. Few studies have considered the impact of the human lung mucosa (alveolar lining
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