Merck
CN
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文件

T32603

Sigma-Aldrich

2-噻吩甲酸

ReagentPlus®, 99%

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经验公式（希尔记法）:
C5H4O2S
CAS号:
527-72-0
分子量:
128.15
Beilstein:
110150
EC 号:
208-423-4
MDL编号:
MFCD00005437
PubChem化学物质编号:
24900123
NACRES:
NA.22

质量水平

100

产品线

ReagentPlus®

检测方案

99%

bp

260 °C (lit.)

mp

125-127 °C (lit.)

SMILES string

OC(=O)c1cccs1

InChI

1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChI key

QERYCTSHXKAMIS-UHFFFAOYSA-N

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相关类别

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Sophie Le Pogam et al.
Journal of virology, 80(12), 6146-6154 (2006-05-30)
Multiple nonnucleoside inhibitor binding sites have been identified within the hepatitis C virus (HCV) polymerase, including in the palm and thumb domains. After a single treatment with a thumb site inhibitor (thiophene-2-carboxylic acid NNI-1), resistant HCV replicon variants emerged that
C Savarin et al.
Organic letters, 3(1), 91-93 (2001-06-30)
[figure: see text] A new methodology for the synthesis of substituted alkynes is described. In the presence of copper(I) thiophene-2-carboxylate (CuTC) or copper (I) 3-methylsalicylate (CuMeSal), the palladium-catalyzed cross-coupling of thioalkyne derivatives with boronic acids affords functionalized alkynes in yields
Mrinal K Bera et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(42), 11838-11843 (2011-09-08)
Herein, we describe our attempts to systematically prepare a series of oligo(2-thienyl)-substituted pyridine derivatives. The crucial starting material, a β-alkoxy-β-ketoenamide, is easily available on a large scale by the reaction of lithiated methoxyallene with thiophene-2-carbonitrile and thiophene-2-carboxylic acid. This three-component
Laval Chan et al.
Bioorganic & medicinal chemistry letters, 14(3), 793-796 (2004-01-27)
The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in Huh-7 cells.
J C Cheminat et al.
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 57(5-6), 307-310 (1981-02-08)
A double blind study of thiophene carboxylate in 32 chronic bronchitis patients, show an improvement of clinical and respiratory condition in the treated group. However, there is no increase in volume of expectoration and no fluidizing. The product acts as
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