W224847
4-萜烯醇
≥95%, FCC, FG
别名:
4-松油烯醇
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关于此项目
经验公式（希尔记法）:
C10H18O
化学文摘社编号:
分子量:
154.25
FEMA Number:
2248
Council of Europe no.:
2229
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
2.072
EC Number:
209-235-5
NACRES:
NA.21
MDL number:
Organoleptic:
woody; earthy; pepper
Grade:
FG, Halal
Biological source:
synthetic
Food allergen:
no known allergens
SMILES string
CC(C)C1(O)CCC(C)=CC1
InChI
1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3
InChI key
WRYLYDPHFGVWKC-UHFFFAOYSA-N
biological source
synthetic
grade
FG, Halal
reg. compliance
EU Regulation 1334/2008 & 872/2012, FCC, FDA 21 CFR 117, FDA 21 CFR 172.515
assay
≥95%
refractive index
n20/D 1.478
bp
88-90 °C
density
0.931 g/mL at 25
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
woody; earthy; pepper
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Application
- 4-松油醇通过p38MAPK/NF-B信号通路轴（signaling pathway axis）抑制IL-13和粘液产生，从而改善小鼠变应性鼻炎和哮喘综合征。: 展示了4-松油醇在呼吸系统疾病治疗中的抗炎和治疗潜力，突出了其在分子水平上的作用机制（Bezerra Barros et al., 2020）。
Biochem/physiol Actions
味道 30ppm
General description
自然发生： 茴香，罗勒，黑加仑，可可，香菜，蔓越莓，葡萄柚，柠檬，酸橙，马郁兰，薄荷油，肉豆蔻和留兰香。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Organoleptic Characteristics of Flavor Materials
Mosciano, G.
Perfumer & Flavorist, 30, 59-59 (2005)
M Miyazawa et al.
Xenobiotica; the fate of foreign compounds in biological systems, 41(12), 1056-1062 (2011-11-08)
The in vitro metabolism of (-)-terpinen-4-ol was examined in human liver microsomes and recombinant enzymes. The biotransformation of (-)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry. (-)-Terpinen-4-ol was found to be oxidized to (-)-(1S,2R,4R)-1,2-epoxy-p-menthan-4-ol, major metabolic product by human liver microsomal
Kotchaphan Chooluck et al.
Planta medica, 78(16), 1761-1766 (2012-10-03)
The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal
Yong Jie Li et al.
Environmental science & technology, 44(14), 5483-5489 (2010-06-17)
We investigated the condensed-phase reactions of biogenic VOCs with C double bond C bonds (limonene, C(10)H(16), and terpineol, C(10)H(18)O) catalyzed by sulfuric acid by both bulk solution (BS) experiments and gas-particle (GP) experiments using a flow cell reactor. Product analysis
Olfa Baâtour et al.
Acta pharmaceutica (Zagreb, Croatia), 62(2), 251-261 (2012-07-04)
O. majorana shoots were investigated for their essential oil (EO) composition. Two experiments were carried out; the first on hydroponic medium in a culture chamber and the second on inert sand in a greenhouse for 20 days. Plants were cultivated
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