Merck
CN

800811O

Avanti

18:1 DG

1-2-dioleoyl-sn-glycerol, neat oil

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别名:
1-2-二-(9Z-十八碳烯酰基)-sn-甘油;DG(18:1(9Z)/18:1(9Z)/0:0); DOG
Empirical Formula (Hill Notation):
C39H72O5
CAS号:
分子量:
620.99
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 10 mg (with screw cap (800811O-10mg))
pkg of 2 × 100 mg (with screw cap (800811O-200mg))
pkg of 5 × 100 mg (with screw cap 800811O-500mg)
pkg of 1 × 25 mg (with screw cap (800811O-25mg))

manufacturer/tradename

Avanti Polar Lipids 800811O

lipid type

neutral glycerides
neutral lipids

运输

dry ice

储存温度

−20°C

InChI

1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3/b19-17+,20-18-/t37-/m0/s1

InChI key

AFSHUZFNMVJNKX-CSWDEDFYSA-N

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此商品
800811C800820P870314C
18:1 DG 1-2-dioleoyl-sn-glycerol, neat oil

Avanti

800811O

18:1 DG

18:1 DG 1-2-dioleoyl-sn-glycerol, chloroform

Avanti

800811C

18:1 DG

18:0 DG 1,2-dioctadecanoyl-sn-glycerol, powder

Avanti

800820P

18:0 DG

18:1 DGS Avanti Polar Lipids 870314C

Avanti

870314C

18:1 DGS

form

liquid

form

liquid

form

powder

form

liquid

packaging

pkg of 1 × 10 mg (with screw cap (800811O-10mg)), pkg of 2 × 100 mg (with screw cap (800811O-200mg)), pkg of 5 × 100 mg (with screw cap 800811O-500mg), pkg of 1 × 25 mg (with screw cap (800811O-25mg))

packaging

pkg of 1 × 5 mL (800811C-10mg), pkg of 1 × 5 mL (800811C-25mg), pkg of 1 × 8 mL (800811C-200mg)

packaging

pkg of 1 × 5 mg (800820P-5mg)

packaging

pkg of 1 × 2.5 mL (870314C-25mg), pkg of 2 × 4 mL (870314C-200mg)

manufacturer/tradename

Avanti Polar Lipids 800811O

manufacturer/tradename

Avanti Polar Lipids 800811C

manufacturer/tradename

Avanti Polar Lipids 800820P

manufacturer/tradename

Avanti Polar Lipids 870314C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

二酰基甘油/甘油二酸酯(DAG)是一种甘油脂,位于质膜上。它由两条脂肪酸链组成,在酯键的帮助下共价连接到单个甘油分子上。

应用

18:1 DG已被用作二酰基甘油O-酰基转移酶1(DGAT1)测定中的二酰基甘油来源。它也被用作底物,以在DGAT-1酶测定中评估化合物作为DGAT-1的潜在抑制剂。它适合与重组蛋白His-AtROP6一起用于脂质-蛋白质覆盖筛选测定。

包装

5 mL带螺旋盖的PTFE小瓶(800811O-200mg)
5 mL带螺旋盖的PTFE小瓶(800811O-10mg)
5 mL带螺旋盖的PTFE小瓶(800811O-25mg)
5 mL带螺旋盖的PTFE小瓶(800811O-500mg)

储存及稳定性

二酰基甘油方便地储存在带有PTFE衬里盖的玻璃小瓶中的氯仿溶液中,温度为-20°C。在这些条件下,酰基迁移最小。处理氯仿溶液时应避免使用塑料。

其他说明

有效浓度:
大多数生物学反应在20至250 μM sn-1,2二辛酰基甘油时饱和。只有sn-1,2异构体似乎具有活性。
注意事项:由于短链二酰基甘油在许多生物系统中模仿促进肿瘤的佛波二酯的作用,因此在处理它们时应格外小心。在清洗或丢弃之前用1N NaOH处理溶液、容器和其他物品会破坏二酰基甘油。
输送至细胞:
使用氮气流干燥氯仿中的二酰基甘油样品。将残留物溶于适当体积的乙醇或DMSO中,然后稀释至所需的水性介质中。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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