CN
所有图片(2)

810331P

Avanti

18:1 Pyrene PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(1-pyrenesulfonyl) (ammonium salt), powder

Empirical Formula (Hill Notation):
C57H89N2O10PS
CAS号:
分子量:
1025.36
NACRES:
NA.25

测定

>99% (TLC)

形式

powder

包装

pkg of 1 × 1 mg (810331P-1mg)

运输

dry ice

储存温度

−20°C

一般描述

Pyrene is made up of four fused benzol rings. It is an apolar molecule. Phosphatidylethanolamine (PE), a phospholipid is found abundantly in mammalian cells. In mammals, 15-25% of the total lipid comprises of PE. It is enriched in the inner leaflet of membranes and is abundant in the inner mitochondrial membrane.

应用

18:1 Pyrene PE may be used:
  • as a quencher of protein intrinsic emission in intrinsic tryptophan quenching assays of membrane proximity
  • to incorporate in vesicle membranes
  • to label vesicles to confirm the presence of hybrid vesicles in flow-cytometric analysis

生化/生理作用

Phosphatidylethanolamine (PE) can serve as a lipid chaperone that supports in the folding of membrane proteins. It plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.

包装

5 mL Amber Glass Screw Cap Vial (810331P-1mg)

Storage Class Code

13 - Non Combustible Solids

分析证书

原产地证书 (CofO)

beta-Carotene-Lipid Interactions in Liposomes with Different Lipid Composition
Advances in pharmacognosy and phytomedicine, 14, 293-307 (2011)
Membrane Fluidity Is a Key Modulator of Membrane Binding, Insertion, and Activity of 5-Lipoxygenase
Pande AH, et al.
Biophysical Journal, 88(6), 4084-4094 (2005)
Ethanolamine and phosphatidylethanolamine: partners in health and disease
Patel D and Witt SN
Oxidative Medicine and Cellular Longevity (2017)
MT1-MMP Binds Membranes by Opposite Tips of Its beta Propeller to Position It for Pericellular Proteolysis
Marcink TC, et al.
Structure, 27(2), 281-292 (2019)
Hybrid, Nanoscale Phospholipid/Block Copolymer Vesicles
Lim SK, et al.
Polymers, 5(3), 1102-1114 (2020)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门