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840037P

Avanti

16:0 PS

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

别名:
1,2-二十六烷酰基-sn-甘油-3-磷酸-L-丝氨酸(钠盐);DPPS;PS(16:0/16:0);110668
Empirical Formula (Hill Notation):
C38H73NO10PNa
CAS号:
分子量:
757.95
NACRES:
NA.25

测定

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)

运输

dry ice

储存温度

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

一般描述

磷脂酰丝氨酸是一种在真核细胞中大量存在的阴离子磷脂。总细胞脂质的10%由磷脂酰丝氨酸组成。O-磷酸-L-丝氨酸是热稳定性底物。

应用

16:0 PS可用于脂质体浮选分析,用于测定其在纯化发动蛋白相关蛋白1(Drp1)之间的相互作用,并可作为制备单层脂质体的脂质混合物的成分。它还被用于通过脂膜水化法制备脂质体。
16:0 PS 已用于测定纯化动力学相关蛋白 1 (Drp1) 和合成脂质体之间互作的分析实验。

生化/生理作用

磷脂酰丝氨酸(PtdSer)参与各种细胞内信号通路。它还在细胞凋亡和血液凝固中起主要作用。

包装

30 mL 螺旋盖棕色宽口瓶 (840037P-500mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-10mg)
20 mL 螺旋盖透明玻璃瓶 (840037P-200mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-25mg)

Storage Class Code

13 - Non Combustible Solids

分析证书

原产地证书 (CofO)

更多文件

Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Chelsea A Kraynak et al.
Acta biomaterialia, 108, 250-260 (2020-04-07)
Macrophages play a critical role in the initiation, maintenance, and resolution of inflammation because of their diverse and plastic phenotypic responses to extracellular stimuli. Inflammatory stimuli drive the recruitment and activation of inflammatory (M1) macrophages, capable of significant cytokine production...
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
Ana Cristina Racca et al.
Frontiers in oncology, 9, 544-544 (2019-07-06)
Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins...
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix...

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