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850345C

Avanti

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

别名:
1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
Empirical Formula (Hill Notation):
C36H72NO8P
CAS号:
分子量:
677.93
NACRES:
NA.25

测定

>99% (TLC)

包装

pkg of 1 × 2.5 mL (850345C-25mg)
pkg of 1 × 20 mL (850345C-500mg)
pkg of 2 × 20 mL (850345C-1g)
pkg of 2 × 4 mL (850345C-200mg)

浓度

10 mg/mL (850345C-25mg)
25 mg/mL (850345C-1g)
25 mg/mL (850345C-200mg)
25 mg/mL (850345C-500mg)

运输

dry ice

储存温度

−20°C

InChI

1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1

InChI key

CITHEXJVPOWHKC-UMSFTDKQSA-N

一般描述

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:
  • in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
  • in labeled vesicle preparation for fluorescence polarization measurements
  • as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

生化/生理作用

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

包装

5 mL Clear Glass Sealed Ampule (850345C-25mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)
5 mL Clear Glass Sealed Ampule (850345C-200mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany

WGK 3

闪点(F)

does not flash

闪点(C)

does not flash

分析证书

原产地证书 (CofO)

更多文件

The Membranes of Cells (2016)
In vitro Membrane Interaction and Liposome Fusion Assays Using Recombinant Hepatitis C Virus Envelope Protein E2
Yelamos B, et al.
Biochimica et biophysica acta. General subjects (2018)
The acceleration of implant osseointegration by liposomal Wnt3a
Popelut A, et al.
Biomaterials, 31(35), 9173-9181 (2010)
Quantitative assays for esterified oxylipins generated by immune cells.
Morgan AH, et al.
Nature Protocols, 5(12), 1919-1931 (2010)
Lipid binding by disordered proteins
Perez Y, et al.
Protocol Exchange, 10 (2013)

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