Merck
CN

850400C

Avanti

22:6 (Cis) PC

1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine, chloroform

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别名:
1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine; PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Empirical Formula (Hill Notation):
C52H80NO8P
CAS号:
分子量:
878.17
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850400C-25mg)
pkg of 5 × 4 mL (850400C-500mg)

manufacturer/tradename

Avanti Polar Lipids 850400C

浓度

10 mg/mL (850400C-25mg)
25 mg/mL (850400C-500mg)

lipid type

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

InChI

1S/C52H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h8-11,14-17,20-23,26-29,32-35,38-41,50H,6-7,12-13,18-19,24-25,30-31,36-37,42-49H2,1-5H3/b10-8-,11-9-,16-14-,17-15-,22-20-,23-21-,28-26-,29-27-,34-32-,35-33-,40-38-,41-39-/t50-/m1/s1

InChI key

XLKQWAMTMYIQMG-SVUPRYTISA-N

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此商品
850461C852472C850472C
22:6 (Cis) PC 1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine, chloroform

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C18(Plasm)-22:6 PC 1-(1Z-octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine, chloroform

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C18(Plasm)-22:6 PC

18:0-22:6 PC 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine, chloroform

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850472C

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form

liquid

form

liquid

form

liquid

form

liquid

packaging

pkg of 1 × 2.5 mL (850400C-25mg), pkg of 5 × 4 mL (850400C-500mg)

packaging

pkg of 1 × 2.5 mL (850461C-25mg)

packaging

pkg of 1 × 5 mL (852472C-5mg)

packaging

pkg of 1 × 2.5 mL (850472C-25mg), pkg of 2 × 20 mL (850472C-1g), pkg of 2 × 4 mL (850472C-200mg)

manufacturer/tradename

Avanti Polar Lipids 850400C

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 852472C

manufacturer/tradename

Avanti Polar Lipids 850472C

concentration

10 mg/mL (850400C-25mg), 25 mg/mL (850400C-500mg)

concentration

10 mg/mL (850461C-25mg)

concentration

1 mg/mL (852472C-5mg)

concentration

10 mg/mL (850472C-25mg), 25 mg/mL (850472C-1g), 25 mg/mL (850472C-200mg)

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

一般描述

22:6 (cis) PC or 1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of docosahexaenic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup. It is an omega-3 lipid.

应用

22:6 (cis) PC or 1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine might be used:
  • in liposomes, to study its effect on membrane vesiculation by dynamin and endophilin
  • in multi-lamellar vesicles (MLVs) to analyze its effect on the biophysical properties of lipid membranes and on its interaction with a fragment of the Aβ peptide
  • in lipid bilayers to study the influence of cholesterol on lateral segregation of saturated and unsaturated phospholipids

包装

5 mL Clear Glass Sealed Ampule (850400C-25mg)
5 mL Clear Glass Sealed Ampule (850400C-500mg)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

危险化学品
易制毒化学品(2类)

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Saturated and unsaturated phospholipids (PLs) can segregate into lateral domains. The preference of cholesterol for saturated acyl chains over monounsaturated, and especially polyunsaturated ones, may also affect lateral segregation. Here we have studied how cholesterol influenced the lateral segregation of
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