Merck
CN

860080P

Avanti

18:1 Lactosyl PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt), powder

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别名:
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)
Empirical Formula (Hill Notation):
C53H103N2O18P
分子量:
1087.36
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 25 mg (860080P-25mg)
pkg of 1 × 5 mg (860080P-5mg)
pkg of 1 × 50 mg (860080P-50mg)

manufacturer/tradename

Avanti Polar Lipids 860080P

运输

dry ice

储存温度

−20°C

SMILES string

[H][C@@](COP(OCCNCC(O)C(O)[C@@H]([C@H](O)CO)O[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C53H100NO18P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-46(59)67-40-42(70-47(60)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)41-69-73(65,66)68-36-35-54-37-43(57)48(61)52(44(58)38-55)72-53-51(64)50(63)49(62)45(39-56)71-53;/h17-20,42-45,48-58,61-64H,3-16,21-41H2,1-2H3,(H,65,66);1H3/b19-17-,20-18-;/t42-,43?,44?,45?,48?,49+,50?,51?,52-,53+;/m1./s1

InChI key

POKKWVSABAYGGQ-GDPHZLNSSA-N

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此商品
852758P850852P852758C
18:1 Lactosyl PE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt), powder

Avanti

860080P

18:1 Lactosyl PE

C18(Plasm)-18:1 PE 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder

Avanti

852758P

C18(血浆)-18:1 PE

18:1 Dimethyl PE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N,N-dimethyl, powder

Avanti

850852P

18:1 Dimethyl PE

C18(Plasm)-18:1 PE 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

Avanti

852758C

C18(Plasm)-18:1 PE

form

powder

form

powder

form

powder

form

liquid

packaging

pkg of 1 × 25 mg (860080P-25mg), pkg of 1 × 5 mg (860080P-5mg), pkg of 1 × 50 mg (860080P-50mg)

packaging

pkg of 1 × 10 mg (852758P-10mg), pkg of 1 × 5 mg (852758P-5mg)

packaging

pkg of 1 × 25 mg (850852P-25mg)

packaging

pkg of 1 × 5 mL (852758C-10mg), pkg of 1 × 5 mL (852758C-5mg)

manufacturer/tradename

Avanti Polar Lipids 860080P

manufacturer/tradename

Avanti Polar Lipids 852758P

manufacturer/tradename

Avanti Polar Lipids 850852P

manufacturer/tradename

Avanti Polar Lipids 852758C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

Phosphatidylethanolamine is a phospholipid and is bound to the biological membranes.

应用

18:1 Lactosyl PE is suitable for the preparation of donor liposomes.

生化/生理作用

Phosphatidylethanolamine has a tendency of binding to proteins and forming a complex of phosphatidylethanolamine-binding protein (PEBP). The binding of an isoform of phosphatidylethanolamine (1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine) to Peroxisome Proliferator-Activated Receptors (PPARs) helps in regulating genes involved in lipid metabolism.

包装

5 mL Clear Glass Sealed Ampule (860080P-25mg)
5 mL Clear Glass Sealed Ampule (860080P-50mg)
5 mL Clear Glass Sealed Ampule (860080P-5mg)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Banfield M J, et al.
Structure, 6(10), 1245-1254 (1998)
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Bockelmann S, et al.
Journal of Lipid Research, 59(3), 515-530 (2018)
Phosphatidylcholine?s functions beyond that of a membrane brick
Furse S and De Kroon AIPM
Molecular Membrane Biology, 32(4), 117-119 (2015)
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction

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