51082
溴己新 盐酸盐
analytical standard
别名:
2-氨基-3,5-二溴-N-环己基-N-甲基苄胺 盐酸盐, N-(2-氨基-3,5-二溴苄基)-N-甲基环己胺 盐酸盐, 溴苄环己铵 盐酸盐
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经验公式（希尔记法）:
C14H20Br2N2 · HCl
化学文摘社编号:
分子量:
412.59
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
210-280-8
Beilstein/REAXYS Number:
4848376
MDL number:
format
neat
Quality Level
InChI key
UCDKONUHZNTQPY-UHFFFAOYSA-N
InChI
1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H
SMILES string
Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2
grade
analytical standard
assay
98.0-102.0% (AT)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
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Application
Bromhexine hydrochloride may be used as a reference standard in the determination of bromhexine hydrochloride in:
- Cough-cold syrup using high performance liquid chromatography (HPLC).
- Pharmaceutical formulations using gas liquid chromatography (GLC) and high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Gas-liquid chromatographic and ion-pair high-performance liquid chromatographic determination of pseudoephedrine hydrochloride and bromhexine hydrochloride in pharmaceuticals.
Rao V E, et al.
Analyst, 112(6), 871-874 (1987)
Simultaneous determination of bromhexine hydrochloride and methyl and propyl p-hydroxybenzoate and determination of dextromethorphan hydrobromide in cough-cold syrup by high-performance liquid chromatography.
Rauha P-J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15(2), 287-293 (1996)
Ryusuke Kajihara et al.
International journal of pharmaceutics, 481(1-2), 132-139 (2015-02-11)
Multiple-unit tablets consisting of polymer-coated microgranules and excipients have a number of advantageous pharmaceutical properties. Polymer-coated microgranules are known to often lose their functionality because of damage to the polymer coating caused by tableting, and the mechanism of polymer coating
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