C0750
咖啡因
powder, ReagentPlus®
别名:
1,3,7-三甲基黄嘌呤
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关于此项目
经验公式（希尔记法）:
C8H10N4O2
化学文摘社编号:
分子量:
194.19
UNSPSC Code:
12352210
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-362-1
Beilstein/REAXYS Number:
17705
MDL number:
Quality Level
product line
ReagentPlus®
form
powder
mp
234-236.5 °C (lit.)
solubility
H2O: 15 mg/mL
SMILES string
CN1C(=O)N(C)c2ncn(C)c2C1=O
InChI
1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
InChI key
RYYVLZVUVIJVGH-UHFFFAOYSA-N
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), PDE4B(5142), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)
General description
咖啡因是一种广泛摄入的药理活性物质。它属于甲基黄嘌呤类。它是一种在咖啡、可可和其他植物中发现的天然生物碱。咖啡因可能与骨质疏松症、心血管疾病风险、心律不齐和胃肠道疾病有关。咖啡因可用于治疗体位性低血压、支气管肺发育不良和早产儿呼吸暂停（AOP）。
Application
咖啡因已被用于：
- 研究其对矮牵牛核荧光的影响
- 在啮齿动物中作为诱导c-fos表达的刺激物
- 作为用于牛卵母细胞体外发育的特定培养基中的一种组分
Biochem/physiol Actions
Caffeine is a natural stimulant that is most commonly found in coffee, tea and various other drinks. It is known for its effect on the central nervous system. It is also associated with insomnia, increased heart rate, digestive issues, creating anxiety and jitteriness. Caffeine is also associated with withdrawal symptoms like headaches, fatigue, irritability.
Features and Benefits
High purity product that can be used readily for HPLC applications along with other research applications.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
监管及禁止进口产品
此项目有
实验方案
Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations
A simple method for immunohistochemical staining of zebrafish brain sections for c-fos protein expression
Chatterjee D, et al.
Zebrafish, 12(6), 414-420 (2015)
Effects of caffeine and chlorogenic acid on propidium iodide accessibility to DNA: consequences on genome size evaluation in coffee tree
Noirot M, et al.
Annals of Botany, 92(2), 259-264 (2003)
Orthostatic hypotension in the elderly: diagnosis and treatment
Gupta V and Lipsitz LA
The American Journal of Medicine, 120(10), 841-847 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C0750-500G | 04061835543137 |
| C0750-1KG | 04061833451564 |
| C0750-5G | 04061835543144 |
| C0750-100G | 04061835543120 |