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E0753

4-乙氧基亚甲基-2-苯基-2-恶唑啉-5-酮

Name: 4-乙氧基亚甲基-2-苯基-2-恶唑啉-5-酮
Brand: SIAL

analytical standard, for drug analysis

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₁NO₃

化学文摘社编号:

15646-46-5

分子量:

217.22

NACRES:

NA.24

PubChem Substance ID:

329798987

UNSPSC Code:

41116107

EC Number:

239-713-9

MDL number:

MFCD00003204

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属性

Quality Level

200

assay

≥90% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

94-96 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

CCO\C=C1/N=C(OC1=O)c2ccccc2

InChI

1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-

InChI key

SJHPCNCNNSSLPL-NTMALXAHSA-N

说明

Application

4-乙氧基亚甲基-2-苯基-2-恶唑啉-5-酮已被用作半抗原化试剂，可在成年斑马鱼肠组织中诱导炎症反应，这可用作克罗恩病和溃疡性结肠炎等两种形式炎症性肠病的基因表达研究的模型。

有关合适仪器技术的更多信息，请参考产品的分析证书。如需进一步支持，请联系技术服务。

Biochem/physiol Actions

噁唑酮敏化剂

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pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P280

Hazard Classifications

Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis.

Amalie W Arildsen et al.

Frontiers in immunology, 12, 650621-650621 (2021-04-06)

Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear. Here we colonized germ-free mice at birth or at one or eight week-of-age to

Dietary prebiotics promote intestinal Prevotella in association with a low-responding phenotype in a murine oxazolone-induced model of atopic dermatitis.

Ann Laigaard et al.

Scientific reports, 10(1), 21204-21204 (2020-12-05)

Atopic dermatitis is a chronic eczema commonly observed among children in Western countries. The gut microbiota is a significant factor in the pathogenesis, and ways to promote intestinal colonizers with anti-inflammatory capabilities are therefore favorable. The present study addressed the

Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers

Haarder S, et al.

The Open Immunology Journal, 6, 154-154 (2016)

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全球贸易项目编号

货号	GTIN
E0753-5G	04061832849706
E0753-1G	04061826035566
E0753-10G	04061832849690