PHR1181
昂丹司琼杂质F
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
2-甲基咪唑, 2-甲基-1,3-氮杂茂
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关于此项目
经验公式（希尔记法）:
C4H6N2
化学文摘社编号:
分子量:
82.10
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
211-765-7
Beilstein/REAXYS Number:
1368
MDL number:
InChI key
LXBGSDVWAMZHDD-UHFFFAOYSA-N
InChI
1S/C4H6N2/c1-4-5-2-3-6-4/h2-3H,1H3,(H,5,6)
SMILES string
Cc1ncc[nH]1
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001320
vapor pressure
<1 mmHg ( 0 °C)
API family
ondansetron
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
267-268 °C (lit.)
mp
142-143 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9000 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Gianantonio Battistuzzi et al.
Journal of the American Chemical Society, 124(19), 5315-5324 (2002-05-09)
Axial iron ligation and protein encapsulation of the heme cofactor have been investigated as effectors of the reduction potential (E degrees ') of cytochrome c through direct electrochemistry experiments. Our approach was that of partitioning the E degrees ' changes
Kiriaki Pegklidou et al.
Journal of agricultural and food chemistry, 56(12), 4482-4490 (2008-05-23)
The potential role of 2-methyl imidazole in improving lycopene production by Blakeslea trispora with regards to yield, selectivity, and safety aspects was investigated in batch culture. Optimization of the bioprocess conditions in terms of (a) (+) and (-) strain ratio
Akito Nakagawa et al.
Bioconjugate chemistry, 17(1), 146-151 (2006-01-19)
We have found that recombinant human serum albumin (HSA) incorporating tailed porphyrinatoiron(II) in the alpha,alpha,alpha,beta-conformer can reversibly bind and release O2 under physiological conditions (pH 7.3, 37 degrees C) like hemoglobin and myoglobin. beta-2-Methylimidazolyl-tailed porphyrinatoirons (6a, 6b) are synthesized via
Jianfeng Li et al.
Inorganic chemistry, 49(5), 2398-2406 (2010-01-29)
The X-ray characterization of the five-coordinate picket-fence porphyrin complex, [Co(TpivPP)(2-MeHIm)], is reported. The complex has the displacement of cobalt from the porphyrin plane = 0.15 A, and Co-N(Im) = 2.145(3) and (Co-N(p))(av) = 1.979(3) A. This five-coordinate complex, in the
Cristina Maccallini et al.
Bioorganic & medicinal chemistry letters, 20(22), 6495-6499 (2010-10-12)
A series of N-substituted acetamidines and 2-methylimidazole derivatives structurally related to W1400 were synthesized and evaluated as Nitric Oxide Synthase (NOS) inhibitors. Analogs with sterically hindering isopropyl and phenyl substituents on the benzylic carbon connecting the aromatic core of W1400
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