产品名称
三氯乙酸, ≥99.0% (titration)
InChI key
YNJBWRMUSHSURL-UHFFFAOYSA-N
InChI
1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
SMILES string
OC(=O)C(Cl)(Cl)Cl
vapor density
<1 (vs air)
vapor pressure
1 mmHg ( 51 °C)
assay
≥99.0% (titration)
form
powder or crystals
refractive index
n20/D 1.62 (lit.)
pH
1 (at 25 °C, 81,7 g/L)
bp
196 °C (lit.)
mp
54-58 °C (lit.)
solubility
H2O: 1 g/10 mL
density
1.62 g/mL at 25 °C (lit.)
functional group
carboxylic acid
chloro
storage temp.
2-8°C
Quality Level
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Application
三氯乙酸(TCA)可作为催化剂合成:
- β-烯胺酮,通过1,3-二羰基化合物与胺的缩合反应。
- 6-氨基-3-甲基-1,4-diphenyl-1,4-二氢吡喃[2,3-c]吡唑-5-腈衍生物,通过乙酸乙酯、苯肼、丙二腈、芳醛的四成分缩合反应.
- 四氢苯并[a]吨酚-11-酮,通过醛、2-萘酚和二酮的三成分反应。
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
存储类别
8B - Non-combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
>235.4 °F - closed cup
flash_point_c
> 113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
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Acta Chimica Slovenica, 60(1), 105-108 (2013)
Efficient, one-pot synthesis of tetrahydrobenzo [a] xanthen-11-ones and dibenzo [a, j] xanthenes using trichloroacetic acid as a solid heterogeneous catalyst under solvent-free conditions
Jaber ZK, et al.
E-Journal of Chemistry, 8(4), 1895-1899 (2011)
Efficient Synthesis of β-Enaminones and β-Enamino Esters Using Tris (Hydrogensulfato) Boron or Trichloroacetic Acid as Catalysts
Karimi-Jaberi Z and Takmilifard Z
European Chemical Bulletin, 2, 211-213 (2013)
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
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Oncotarget, 5(8), 2052-2064 (2014-06-07)
Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an interferon (IFN)-γ-inducible enzyme that degrades tryptophan into kynurenine, which, in turn, inhibits effector T cells and promotes regulatory T-cell (Treg) differentiation. It
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