32301
乙酸铵
puriss. p.a., ACS reagent, reag. Ph. Eur., ≥98%
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关于此项目
线性分子式:
CH3CO2NH4
化学文摘社编号:
分子量:
77.08
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39021908
UNSPSC Code:
12352300
EC Number:
211-162-9
MDL number:
Beilstein/REAXYS Number:
4186741
Assay:
≥98%
Form:
solid
产品名称
乙酸铵, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥98%
InChI key
USFZMSVCRYTOJT-UHFFFAOYSA-N
InChI
1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
SMILES string
N.CC(O)=O
grade
ACS reagent
puriss. p.a.
agency
reag. Ph. Eur.
vapor pressure
<0.001 hPa
assay
≥98%
form
solid
impurities
≤0.005% KMnO4 red. matter (as O)
≤2% water (Karl Fischer)
≤5 mg/kg heavy metals (as Pb)
ign. residue
≤0.01%
pH
6.7-7.3 (25 °C, 5% in water)
mp
110-112 °C (dec.) (lit.)
anion traces
chloride (Cl-): ≤5 mg/kg
nitrate (NO3-): ≤10 mg/kg
sulfate (SO42-): ≤10 mg/kg
cation traces
Ca: ≤10 ppm
Cd: ≤2 ppm
Co: ≤5 ppm
Cr: ≤5 ppm
Cu: ≤2 ppm
Fe: ≤5 ppm
K: ≤50 ppm
Mg: ≤2 ppm
Mn: ≤5 ppm
Na: ≤50 ppm
Ni: ≤5 ppm
Pb: ≤2 ppm
Zn: ≤2 ppm
Quality Level
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Application
在流动相中使用乙酸铵 HPLC 法测定 e zetimibe 及其代谢产物。它可用于制备苯并噻啶唑和维甲胺唑。
General description
乙酸铵为无色吸湿性固体。可由冰醋酸与氨水或碳酸铵反应制得。它是 Pd/C 催化苄基醚氢解反应的潜在抑制剂。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Anima Ghosal et al.
Drug metabolism and disposition: the biological fate of chemicals, 32(3), 314-320 (2004-02-24)
Ezetimibe [1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone] (Zetia; Schering-Plough, Kenilworth, NJ) is the first in a new class of cholesterol-lowering agents known as cholesterol absorption inhibitors. The objective of this study was to identify the isoform(s) of human liver and intestinal UDP-glucuronosyltransferase (UGT) enzymes responsible
Reactions of phenanthraquinone and retenequinone with aldehydes and ammonium acetate in acetic acid solution1.
Steck EA and Day AR.
Journal of the American Chemical Society, 65(3), 452-456 (1943)
Selective inhibition of benzyl ether hydrogenolysis with Pd/C due to the presence of ammonia, pyridine or ammonium acetate.
Sajiki H.
Tetrahedron Letters, 36(20), 3465-3468 (1995)
M Athar Masood et al.
Basic & clinical pharmacology & toxicology, 127(6), 533-550 (2020-11-03)
Urine drug testing (UDT) is an important analytical/bio-analytical technique that has inevitably become an integral and vital part of a testing programme for diagnostic purposes. This manuscript presents a tailor-made LC-MS/MS quantitative assay method development and validation for a custom
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