79710
O-磷酸-DL-丝氨酸
≥98.0% (NT), suitable for cell culture
别名:
DL-2-氨基-3-羟基丙酸3-磷酸, DL-SOP, DL-丝氨酸单磷酸
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关于此项目
经验公式（希尔记法）:
C3H8NO6P
化学文摘社编号:
分子量:
185.07
Beilstein:
1726828
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
产品名称
O-磷酸-DL-丝氨酸, ≥98.0% (NT)
方案
≥98.0% (NT)
表单
powder or crystals
技术
cell culture | mammalian: suitable
杂质
≤0.5% free serine (TLC)
≤1% water
颜色
white to faint beige
SMILES字符串
NC(COP(O)(O)=O)C(O)=O
InChI
1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)
InChI key
BZQFBWGGLXLEPQ-UHFFFAOYSA-N
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相关类别
生化/生理作用
O-磷酸-DL-丝氨酸（pSer）用于研究非酶性氨基磷脂糖基化。
O-磷酸丝氨酸可用于通过O-磷酰基-tRNA：硒代半胱氨酰-tRNA合酶（SepSecS）催化的O-磷酸丝氨酸（Sep）的tRNA依赖性转化进行半胱氨酸和硒代半胱氨酸（Sec）的生物合成的替代途径中。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Yuhei Araiso et al.
Nucleic acids research, 36(4), 1187-1199 (2007-12-26)
The micronutrient selenium is present in proteins as selenocysteine (Sec). In eukaryotes and archaea, Sec is formed in a tRNA-dependent conversion of O-phosphoserine (Sep) by O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SepSecS). Here, we present the crystal structure of Methanococcus maripaludis SepSecS complexed with
Zejuan Sheng et al.
Science translational medicine, 4(164), 164ra161-164ra161 (2012-12-18)
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common cause of familial Parkinson's disease (PD). Although biochemical studies have shown that certain PD mutations confer elevated kinase activity in vitro on LRRK2, there are no methods
Anselm Sauerwald et al.
Science (New York, N.Y.), 307(5717), 1969-1972 (2005-03-26)
Several methanogenic archaea lack cysteinyl-transfer RNA (tRNA) synthetase (CysRS), the essential enzyme that provides Cys-tRNA(Cys) for translation in most organisms. Partial purification of the corresponding activity from Methanocaldococcus jannaschii indicated that tRNA(Cys) becomes acylated with O-phosphoserine (Sep) but not with
Seong-Jun Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6413-6418 (2014-04-16)
Mitochondrial dynamics is crucial for the regulation of cell homeostasis. Our recent findings suggest that hepatitis C virus (HCV) promotes Parkin-mediated elimination of damaged mitochondria (mitophagy). Here we show that HCV perturbs mitochondrial dynamics by promoting mitochondrial fission followed by
Pengcheng Wang et al.
Plant physiology, 161(3), 1392-1408 (2013-01-10)
Reactive oxygen species (ROS) have been characterized as both important signaling molecules and universal stressors that mediate many developmental and physiological responses. So far, details of the transcriptional mechanism of ROS-responsive genes are largely unknown. In the study reported here
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