General description
磷酸酶抑制剂混合液 1 包括将抑制碱性磷酸酶的 L -同工酶以及丝氨酸/苏氨酸蛋白磷酸酶（如 PP1 和 PP2A）的抑制剂混合物。本品含微囊藻毒素LR、斑蝥素和（−）-p-溴四唑。磷酸酶抑制剂混合液1 已被替换为 P0044。
Application
磷酸酶抑制剂混合液1 已被用于核蛋白分离和电泳迁移率变动分析（EMSA）以激活连环链蛋白。它也已用于蛋白质印迹分析。
Biochem/physiol Actions
磷酸酶是许多重要生物过程的活性调节剂。小分子对磷酸酶的抑制有助于研究其生物学作用。
Preparation Note
推荐的用法是 100 倍稀释。
Analysis Note
检测牛肝脏、人胎盘和兔肌肉等动物组织的细胞提取物，以及 A431 和 Jurkat 细胞系的提取物。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F
flash_point_c
87 °C
法规信息
高风险级别生物产品--毒素类产品
此项目有
Class III β-tubulin expression and in vitro resistance to microtubule targeting agents.
Stengel C, et al.
British Journal of Cancer, 102(2), 316-316 (2010)
Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration.
Nakao S, et al.
Investigative Ophthalmology & Visual Science, 53(7), 3296-3302 (2012)
X Zhao et al.
Mucosal immunology, 10(6), 1553-1568 (2017-04-13)
Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate that necrosis of Mtb-infected Mϕ is dependent on the action of the cytosolic Receptor Interacting Protein Kinase 3 (RIPK3) and
Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma.
Zeng G, et al.
Neoplasia, 8(4), 279-289 (2006)
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis.
Noren M A, et al.
Proceedings of the National Academy of Sciences of the USA, 103(28), 10606-10611 (2006)
商品
The use of phosphatase inhibitors is critical for all types of phosphorylation studies. Compare phosphatase inhibitor cocktails to select the best one for your research.
磷酸酶抑制剂对于所有类型的磷酸化研究都至关重要。对比磷酸酶抑制剂混合物，选择更适合您的研究的产品。
相关内容
This phosphataseinhibitor cocktail has been optimized and tested forL-isozymes of alkaline phosphatase as well asserine/threonine protein phosphatases, such as proteinphosphatases 1 and 2A.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P2850-5ML | 04061838164469 |
| P2850-1ML | 04061838355430 |
| P2850-0.3ML | 04061837898747 |
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