assay
≥98.0%
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycoplasma
mode of action
DNA synthesis | interferes
SMILES string
CC(=O)NS(=O)(=O)c1ccc(N)cc1
InChI
1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
InChI key
SKIVFJLNDNKQPD-UHFFFAOYSA-N
General description
Chemical structure: sulfonamide
Application
Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.
Biochem/physiol Actions
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Packaging
100G,500G
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids
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警示词
Warning
危险代码
Hazard Classifications
Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
存储类别
11 - Combustible Solids
怎么回事?
WGK 2
PPE(个人防护设备)
Eyeshields, Gloves, type N95 (US)
