一般描述
卵类粘蛋白或胰蛋白酶抑制剂是大多数禽蛋白中富含的蛋白质。鸡蛋白约由186个氨基酸残基组成，且高度糖基化。三个串联的结构域均与胰蛋白酶抑制剂同源。其免疫原性很高，而且可能是大多数鸡蛋过敏的原因。
应用
来自鸡蛋白的胰蛋白酶抑制剂已被用于：
- 终止蛋白水解反应
- 在OVO-1溶液中研磨细胞悬浮液以分离视网膜
- 用于皮质解离的磷酸盐缓冲液
生化/生理作用
卵类粘蛋白具有胰蛋白酶抑制剂活性。它有多个可以与免疫球蛋白E（IgE）结合的构象和线性表位。它稳定性高，可耐受加热和蛋白水解。
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物来源生物产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Immunopanning purification and long-term culture of human retinal ganglion cells
Zhang XM, et al.
Molecular Vision, 16, 2867-2867 (2010)
Ovomucoid specific immunoglobulin E as a predictor of tolerance to cooked egg
Bartnikas LM, et al.
Allergy & rhinology (Providence, R.I.), 6(3), ar-2015 (2015)
Meeyong Shin et al.
Allergy, asthma & immunology research, 5(1), 42-47 (2013-01-02)
It is known that ovomucoid, an egg allergen, is heat resistant and remains soluble after heating. However, a recent study showed that the antigenic activity of ovomucoid could be reduced by heating when egg white (EW) was mixed with wheat
ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells
Jiang HF, et al.
Journal of virology, 91(12) (2017)
Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential
Ferree C, et al.
Faseb Journal (2015)
实验方案
This technical article described the Enzymatic Assay of Trypsin Inhibitor.
Chromatograms
application for HPLC
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