A2252
腺苷-5'-单磷酸 一水合物
≥97%, from yeast, powder
别名:
5′-AMP, 5′-腺苷酸, A-5′-P, AMP
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H14N5O7P · H2O
化学文摘社编号:
分子量:
365.24
Beilstein:
54612
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51
产品名称
腺苷-5'-单磷酸 一水合物, from yeast, ≥97%
生物来源
yeast
质量水平
方案
≥97%
表单
powder
溶解性
1 M NH4OH: soluble 50 mg/mL, clear, colorless
H2O: soluble (with addition of mild alkali)
储存温度
−20°C
SMILES字符串
O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP(O)(O)=O.O
InChI
1S/C10H14N5O7P.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1H2/t4-,6-,7-,10-;/m1./s1
InChI key
ZOEFQKVADUBYKV-MCDZGGTQSA-N
正在寻找类似产品? 访问 产品对比指南
应用
5′-单磷酸腺苷（5′-AMP）适合用作
- 合成腺苷-5′-磷酰咪唑啉的试剂
- 合成支链多糖的聚合反应中磷酸化酶b的活化剂
- 内源性NMN腺苷酰转移酶（NMNAT，将NMN转化成NAD+）的活性抑制剂
生化/生理作用
5′-单磷酸腺苷（5′-AMP）本身具有许多用途。5′-AMP是一类称为AMP活化蛋白激酶（AMPK）的蛋白激酶的激活剂。AMP可抑制AMPK去磷酸化，促进上游激酶对AMPK磷酸化。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Bei Liu et al.
Nature communications, 12(1), 5201-5201 (2021-09-02)
N6-methyladenosine (m6A) is a post-transcriptional modification that controls gene expression by recruiting proteins to RNA sites. The modification also slows biochemical processes through mechanisms that are not understood. Using temperature-dependent (20°C-65°C) NMR relaxation dispersion, we show that m6A pairs with
Physical properties and structure of enzymatically synthesized amylopectin analogs
Ciric, Jelena, et al.
Starch/Staerke, 65, 1061-1068 (2013)
Marianne Suter et al.
The Journal of biological chemistry, 281(43), 32207-32216 (2006-09-01)
AMP-activated protein kinase (AMPK) is a heterotrimeric protein kinase that is crucial for cellular energy homeostasis of eukaryotic cells and organisms. Here we report on the activation of AMPK alpha1beta1gamma1 and alpha2beta2gamma1 by their upstream kinases (Ca(2+)/calmodulin-dependent protein kinase kinase-beta
5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes.
Tsuchiya Y, Denison FC, et al.
Bioscience Reports, 32(2), 197-213 (2011)
Irina S Balan et al.
Brain research, 1316, 112-119 (2009-12-29)
A histo-enzymatic technique for visualizing and quantifying endogenous NAD(H) in brain tissue was developed, based on coupled enzymatic cycling reactions that reduce nitrotetrazolium blue chloride to produce formazan. Conditions were used where the endogenous level of nicotinamide adenine dinucleotides (NAD(H))
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持