方案
≥99% (TLC)
表单
powder
溶解性
water: 100 mg/mL, clear to slightly hazy, colorless
储存温度
−20°C
SMILES字符串
[Cl-].CC(=O)SCC[N+](C)(C)C
InChI
1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
GZYVLKKMMDFCKR-UHFFFAOYSA-M
基因信息
human ... ACHE(43)
应用
氯化乙酰胆碱用于确定精液外泌体(SE)中乙酰胆碱酯酶的活性。也可用作乙酰胆碱酯酶的底物,对其动力学参数进行微量量热研究。
生化/生理作用
乙酰胆碱酯酶底物和烟碱型乙酰胆碱受体激动剂。
乙酰胆碱酯酶(AChE)酶在神经传递过程中起着重要的生理作用。
警示用语:
Danger
危险声明
危险分类
Eye Dam. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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The marine secondary metabolite stryphnusin (1) was isolated from the boreal sponge Stryphnus fortis, collected off the Norwegian coast. Given its resemblance to other natural acetylcholinesterase antagonists, it was evaluated against electric eel acetylcholinesterase and displayed inhibitory activity. A library
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Non-selective inhibitors of cholinesterases (ChEs) are clinically used for treatment of myasthenia gravis (MG). While being generally safe, they cause numerous adverse effects including induction of hyperactivity of urinary bladder and intestines affecting quality of patients life. In this study
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Defined as a state function representing an inhibitor's absolute affinity for its target enzyme, the experimentally determined enzyme inhibition constant (K
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