B8271
Bromoacetic acid N-hydroxysuccinimide ester
≥95%, powder
别名:
2,5-Dioxopyrrolidin-1-yl 2-bromoacetate, N-Hydroxysuccinimide bromoacetate
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关于此项目
经验公式（希尔记法）:
C6H6BrNO4
化学文摘社编号:
分子量:
236.02
NACRES:
NC.07
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥95%
Form:
powder
Quality Segment
assay
≥95%
form
powder
reaction suitability
reagent type: cross-linking reagent
solubility
acetone: 25 mg/mL, DMF: soluble
functional group
NHS ester
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(N1OC(CBr)=O)CCC1=O
InChI
1S/C6H6BrNO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
InChI key
NKUZQMZWTZAPSN-UHFFFAOYSA-N
Application
A heterobifunctional cross-linking reagent which allows bromoacetylation of primary amine groups followed by coupling to sulfhydryl-containing compounds. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. The second reaction results in thioether bonding in pH range 7.0-8.0.
Disclaimer
The bromoacetyl group is light sensitive.
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves