D6128
αβ二氢胆固醇
≥95%
别名:
β-胆甾醇, 3β-羟基-5α-胆甾烷, 二氢胆甾醇
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关于此项目
经验公式（希尔记法）:
C27H48O
化学文摘社编号:
分子量:
388.67
Beilstein:
2418594
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.28
生物来源
synthetic (organic)
方案
≥95%
表单
powder
运输
ambient
储存温度
room temp
SMILES字符串
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key
QYIXCDOBOSTCEI-QCYZZNICSA-N
基因信息
human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)
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应用
使用 HPLC，将 5α-胆甾烷-3β-醇用作脂质分析的标准。
生化/生理作用
5α-胆甾烷-3β-醇通过肠道微生物的作用来源于胆固醇。已知在存在钠离子的情况下可诱导兔胆石形成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
BIOSYNTHESIS OF 5-ALPHA-CHOLESTAN-3-BETA-OL IN THE RABBIT AND GUINEA PIG.
S SHEFER et al.
The Journal of biological chemistry, 239, 1731-1736 (1964-06-01)
Anna Bertolini et al.
American journal of physiology. Gastrointestinal and liver physiology, 316(3), G404-G411 (2019-01-18)
The gastrointestinal phenotype of cystic fibrosis (CF) features intestinal bile acid (BA) malabsorption, impaired intestinal farnesoid X receptor (FXR) activation, and consequently reduced fibroblast growth factor 19 (FGF19, FGF15 in mice) production. The osmotic laxative polyethylene glycol (PEG) has been
IDENTIFICATION OF ALLODEOXYCHOLIC ACID AS THE MAJOR COMPONENT OF GALLSTONES INDUCED IN THE RABBIT BY 5-ALPHA-CHOLESTAN-3-BETA-OL.
A F HOFMANN et al.
The Journal of biological chemistry, 239, 2813-2821 (1964-09-01)
J Giacometti
The Analyst, 126(4), 472-475 (2001-05-09)
In general, analyses for aliphatic alcohols, sterols and tocopherols in vegetable oils are performed separately. A simple and reliable procedure is presented for the quantification of the alkanols, squalene, alpha-tocopherol and sterols in olive oils by a direct method involving
Benjamin L Stottrup et al.
Biophysical journal, 90(9), 3176-3183 (2006-02-08)
We investigate the miscibility phase behavior of lipid monolayers containing a wide variety of sterols. Six of the sterols satisfy a definition from an earlier study of "membrane-active sterols" in bilayers (cholesterol, epicholesterol, lathosterol, dihydrocholesterol, ergosterol, and desmosterol), and six
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