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Merck
CN

D6128

αβ二氢胆固醇

≥95%

别名:

β-胆甾醇, 3β-羟基-5α-胆甾烷, 二氢胆甾醇

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关于此项目

经验公式(希尔记法):
C27H48O
化学文摘社编号:
分子量:
388.67
UNSPSC Code:
12352211
NACRES:
NA.28
PubChem Substance ID:
EC Number:
201-315-8
Beilstein/REAXYS Number:
2418594
MDL number:
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产品名称

αβ二氢胆固醇, ≥95%

InChI

1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

QYIXCDOBOSTCEI-QCYZZNICSA-N

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

biological source

synthetic (organic)

assay

≥95%

form

powder

shipped in

ambient

storage temp.

room temp

Quality Level

Gene Information

human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)

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Application

使用 HPLC,将 5α-胆甾烷-3β-醇用作脂质分析的标准。

Biochem/physiol Actions

5α-胆甾烷-3β-醇通过肠道微生物的作用来源于胆固醇。已知在存在钠离子的情况下可诱导兔胆石形成。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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J Giacometti
The Analyst, 126(4), 472-475 (2001-05-09)
In general, analyses for aliphatic alcohols, sterols and tocopherols in vegetable oils are performed separately. A simple and reliable procedure is presented for the quantification of the alkanols, squalene, alpha-tocopherol and sterols in olive oils by a direct method involving
IDENTIFICATION OF ALLODEOXYCHOLIC ACID AS THE MAJOR COMPONENT OF GALLSTONES INDUCED IN THE RABBIT BY 5-ALPHA-CHOLESTAN-3-BETA-OL.
A F HOFMANN et al.
The Journal of biological chemistry, 239, 2813-2821 (1964-09-01)
Benjamin L Stottrup et al.
Biophysical journal, 90(9), 3176-3183 (2006-02-08)
We investigate the miscibility phase behavior of lipid monolayers containing a wide variety of sterols. Six of the sterols satisfy a definition from an earlier study of "membrane-active sterols" in bilayers (cholesterol, epicholesterol, lathosterol, dihydrocholesterol, ergosterol, and desmosterol), and six
Morgane Derrien et al.
Journal of agricultural and food chemistry, 59(13), 7294-7302 (2011-05-25)
Thirty-five samples of cow feces (cowpat and cow manure) and pig slurries subjected to different treatment processes and different storage times before land spreading were extracted and analyzed by gas chromatography-mass spectrometry to determine their fecal stanol profiles. The fresh
Anna Bertolini et al.
American journal of physiology. Gastrointestinal and liver physiology, 316(3), G404-G411 (2019-01-18)
The gastrointestinal phenotype of cystic fibrosis (CF) features intestinal bile acid (BA) malabsorption, impaired intestinal farnesoid X receptor (FXR) activation, and consequently reduced fibroblast growth factor 19 (FGF19, FGF15 in mice) production. The osmotic laxative polyethylene glycol (PEG) has been

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