D8388
庚二酰亚胺酸二甲酯二盐酸盐 二盐酸盐
powder
别名:
DMP, Dimethyl pimelinediimidate 二盐酸盐
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关于此项目
线性分子式:
[CH3OC(=NH)CH2CH2]2CH2 · 2HCl
化学文摘社编号:
分子量:
259.17
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
261-320-6
MDL number:
产品名称
庚二酰亚胺酸二甲酯二盐酸盐 二盐酸盐, powder
InChI key
LRHXBHUTQWIZTN-UHFFFAOYSA-N
InChI
1S/C9H18N2O2.2ClH/c1-12-8(10)6-4-3-5-7-9(11)13-2;;/h10-11H,3-7H2,1-2H3;2*1H
SMILES string
Cl.Cl.COC(=N)CCCCCC(=N)OC
form
powder
reaction suitability
reagent type: cross-linking reagent
solubility
H2O: 10 mg/mL
storage temp.
−20°C
Quality Level
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Application
庚二亚氨酸二甲酯二盐酸盐可用于开发一种直接从人类粪便样品中分离高纯度比氏肠胞（Enterocytozoon bieneusi）孢子的技术，为研究这种寄生虫开创出新的方法。
Disclaimer
该试剂在中性pH下易于水解。
General description
庚二亚氨酸二甲酯二盐酸盐是一种同双功能交联剂，适用于交联、蛋白相互作用和蛋白修饰。通常，在pH7.0-10.0的范围内，与伯胺反应形成脒键。
Other Notes
注意，脒键保留了原始的伯胺正电荷。 包含七个原子连接子。
signalword
Warning
hcodes
Hazard Classifications
Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
K Brew et al.
The Journal of biological chemistry, 250(4), 1434-1444 (1975-02-25)
The cross-linking of the two components of lactose synthetase, alpha-lactalbumin and a galactosyltransferase, with dimethylpimelimidate was examined. The extent of the cross-linking at pH 8.1 was found to be dependent upon the presence of substrates or inhibitors for the galactosyltransferase.
I Accoceberry et al.
Journal of clinical microbiology, 39(5), 1947-1951 (2001-04-28)
An original, reliable, and reproducible method for the purification of Enterocytozoon bieneusi spores from human stools is described. We recently reported the production of a species-specific monoclonal antibody (MAb) 6E52D9 immunoglobulin G2a (IgG2a) raised against the exospore of E. bieneusi
G B Karlsson et al.
Analytical biochemistry, 199(2), 219-222 (1991-12-01)
A method is described for the use of magnetic beads as a solid phase for the immunoprecipitation of labeled proteins. The anti-human transferrin receptor monoclonal antibody OKT-9 has been coupled to sheep anti-mouse IgG1-coated magnetic beads using the crosslinking agent
Kevin Michael Boehm et al.
BMC bioinformatics, 20(1), 7-7 (2019-01-07)
To further our understanding of immunopeptidomics, improved tools are needed to identify peptides presented by major histocompatibility complex class I (MHC-I). Many existing tools are limited by their reliance upon chemical affinity data, which is less biologically relevant than sampling
Semisynthetic fluorohydrolases prepared by chemical modification of ribonuclease.
David, E., et al.
Enz. Microbiol. Technol., 14, 885-892 (1992)
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