E1631
β-雌二醇 17-戊酸酯
≥98% (HPLC), powder
别名:
1,3,5(10)-雌三烯-3,17β-二醇 17-戊酸酯
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关于此项目
经验公式（希尔记法）:
C23H32O3
化学文摘社编号:
分子量:
356.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
213-559-2
MDL number:
Beilstein/REAXYS Number:
2480357
产品名称
β-雌二醇 17-戊酸酯, ≥98%
biological source
synthetic
Quality Level
assay
≥98%
form
powder
technique(s)
ELISA: suitable
solubility
acetone: 25 mg/mL, hazy, colorless
shipped in
ambient
storage temp.
room temp
SMILES string
CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C
InChI
1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3
InChI key
RSEPBGGWRJCQGY-UHFFFAOYSA-N
General description
β-Estradiol 17-valerate is a synthetic estrogen.
Application
β-Estradiol 17-valerate has been used:
- in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions
- to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice
- to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model
Biochem/physiol Actions
Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
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This randomized controlled trial analyses the ability to control the oocyte retrieval schedule of gonadotrophin-releasing hormone antagonist cycles through the administration of oestradiol valerate during the luteo-follicular transition period prior to the initiation of ovarian stimulation. Eighty-six women undergoing ovarian
Marika Christina Möller et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 29(2), 173-176 (2012-10-26)
Both estrogen and testosterone insufficiency has been associated with reduced psychological well-being including fatigue. However, hormonal replacement studies on fatigue are rare. Therefore, we wanted to study the effect of testosterone and estrogen replacement therapy on cognitive fatigue and the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E1631-1G | 04061833602010 |