F0881
Fusidic acid sodium salt
≥98% (TLC), Bacterial protein synthesis inhibitor
别名:
Fucidin
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关于此项目
线性分子式:
C31H47O6Na
化学文摘社编号:
分子量:
538.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
212-030-3
MDL number:
Assay:
≥98% (TLC)
产品名称
Fusidic acid sodium salt, ≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
solubility
H2O: soluble
antibiotic activity spectrum
neoplastics
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].C[C@@H]1[C@H](O)CC[C@@]2(C)C1CC[C@@]3(C)C2[C@H](O)CC4\C([C@H](C[C@]34C)OC(C)=O)=C(/CC\C=C(\C)C)C([O-])=O
InChI
1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1
InChI key
HJHVQCXHVMGZNC-JCJNLNMISA-M
General description
Fusidic acid is an antibiotic substance, resembling the structure of a steroid. It belongs to the class of fusidanes.
Application
Fusidic acid sodium salt has been used to study the effects of three-drug combinations on the growth rate of a bacterium, wild-type Escherichia coli. It is also used to study the in vitro susceptibility of dog-derived European methicillin-resistant Staphylococcus pseudintermedius and Staphylococcus aureus strains and their methicillin-susceptible counterparts.
Biochem/physiol Actions
Fusidic acid possesses antimicrobial action against skin pathogens. It is highly specific to Staphylococcus aureus. It is therefore used for treating infected traumatic wounds, folliculitis, furunculosis, impetigo, erythrasma and abscesses.
Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Suppresses nitric oxide lysis of pancreatic islet cells; inhibits protein synthesis in prokaryotes.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
警示词
Warning
危险代码
预防性声明
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
dust mask type N95 (US), Eyeshields, Gloves