F7129
5-氟胞嘧啶
nucleoside analog
别名:
4-氨基-5-氟-2(1H)-嘧啶酮, 氟胞嘧啶
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关于此项目
经验公式（希尔记法）:
C4H4FN3O
化学文摘社编号:
分子量:
129.09
Beilstein:
127285
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.32
质量水平
方案
≥99% (TLC)
表单
powder
分子量
129.09 g/mol
浓度
≤100% (Flucytosine)
颜色
white to off-white
mp
298-300 °C (dec.) (lit.)
溶解性
formic acid: 50 mg/mL, colorless to faintly yellow
λmax
285-287 nm
荧光
(EmM Anhydrous 8.8 - 9.4, pH 1.0)
抗生素抗菌谱
fungi
作用机制
DNA synthesis | interferes
protein synthesis | interferes
储存温度
2-8°C
SMILES字符串
NC1=NC(=O)NC=C1F
InChI
1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
InChI key
XRECTZIEBJDKEO-UHFFFAOYSA-N
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一般描述
化学结构：核苷
应用
用于 TMP 生物合成研究。
生化/生理作用
具有抗真菌活性的核苷类似物。 5-FC由胞嘧啶脱氨基酶脱氨，可产生5-氟尿嘧啶，导致RNA密码错编。 5-氟尿嘧啶可抑制DNA和RNA的合成，干扰核糖体蛋白质合成。
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