G4796
京尼平
≥98% (HPLC), powder, insulin stimulator
别名:
（1S，2R，6S）-2-羟基-9-（羟甲基）-3-氧杂二环[4.3.0]壬-4，8-二烯-5-羧酸甲酯
Product Name
京尼平, ≥98% (HPLC), powder
质量水平
方案
≥98% (HPLC)
表单
powder
溶解性
DMSO: ≥25 mg/mL
H2O: insoluble
SMILES字符串
COC(=O)C1=CO[C@@H](O)C2C1CC=C2CO
InChI
1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChI key
AZKVWQKMDGGDSV-BCMRRPTOSA-N
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相关类别
一般描述
京尼平是一种天然的交联剂，从栀子果实中提取。它可以防止脂质过氧化和一氧化氮的产生。京尼平保护海马神经元免受阿尔茨海默氏症淀粉样β蛋白的毒性。它具有抗炎和抗血管生成的作用。京尼平参与药物输送系统。
应用
京尼平已被用于：
- 化学敏感性测定
- 制备重组人（rh）- 多基因成釉细胞相关蛋白（ODAM）- 浸渍胶原凝胶和体外矿化试验
- 京尼平凝胶制剂
生化/生理作用
京尼平以 UCP2 依赖性方式刺激胰岛素分泌（解偶联蛋白 2）。
京尼平以 UCP2 依赖性方式刺激胰岛素分泌（解偶联蛋白 2）。 京尼平是蛋白质、胶原蛋白、明胶和壳聚糖交联剂。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
UCP2 expression may represent a predictive marker of neoadjuvant chemotherapy effectiveness for locally advanced uterine cervical cancer
Imai K, et al.
Oncology Letters, 14(1), 951-957 (2017)
Ting Ting Lau et al.
Biomedical materials (Bristol, England), 7(6), 065003-065003 (2012-11-03)
Primary hepatocyte is probably the preferred cell for cell therapy in liver regeneration. However, its non-ideal proliferation capacity and rapid loss of phenotype during 2D culture compromises the quality and quantity of the transplanted hepatocytes, resulting in variable success rates
Michael E Frohbergh et al.
Biomaterials, 33(36), 9167-9178 (2012-10-02)
Reconstruction of large bone defects remains problematic in orthopedic and craniofacial clinical practice. Autografts are limited in supply and are associated with donor site morbidity while other materials show poor integration with the host's own bone. This lack of integration
Effect of Sulfuric Acid Concentration on Radiological Properties of Genipin Gel Dosimeter
Al-Jarrah A, et al.
International Journal of Chemistry (Canadian Center of Science and Education), 2, 2320-4087 (2014)
Using dairy ingredients to produce edible films and biodegradable packaging materials
Tomasula PM
Dairy-Derived Ingredients: Food and Nutraceutical Uses, 589-624 (2009)
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