Merck
CN
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文件

G7251

Sigma-Aldrich

甘氨酸酐

cyclic dipeptide

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别名:
2,5-二酮哌嗪, 2,5-哌嗪二酮
经验公式（希尔记法）:
C4H6N2O2
CAS号:
106-57-0
分子量:
114.10
Beilstein:
112112
EC 号:
203-411-5
MDL编号:
MFCD00006009
eCl@ss:
32160406
PubChem化学物质编号:
24895298
NACRES:
NA.26

检测方案

≥99% (TLC)

形式

powder

颜色

white

mp

>300 °C (lit.)

SMILES string

O=C1CNC(=O)CN1

InChI

1S/C4H6N2O2/c7-3-1-5-4(8)2-6-3/h1-2H2,(H,5,8)(H,6,7)

InChI key

BXRNXXXXHLBUKK-UHFFFAOYSA-N

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相关类别

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Liyun Zhang et al.
Amino acids, 43(1), 279-287 (2011-09-16)
Cyclic dipeptides, due to their chemical properties and various bioactivities, are very attractive for medicinal chemistry. Fragmentations of three simple cyclic dipeptides including cyclo(Gly-Gly), cyclo(Ala-Ala) and cyclo(Gly-Val) in the gas-phase are determined with synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry
R Shukla et al.
Peptides, 15(8), 1471-1474 (1994-01-01)
Central administration of exogenous cyclo(His-Pro) (CHP) is known to produce hypothermia in rodents. In the present study, we examined the role of endogenous CHP in cold-induced hypothermia in the desert rat, Mastomys natalensis. The results of these studies show that
A K Szardenings et al.
Journal of medicinal chemistry, 41(13), 2194-2200 (1998-06-19)
The discovery of a novel series of heterocyclic matrix metalloproteinase (MMPs) inhibitors is described. Published crystal structures of peptidyl hydroxamates bound to MMPs were the basis for the rational design of diketopiperazine (DKP) inhibitors. Combinatorial libraries were prepared and evaluated
M Prudel et al.
Die Nahrung, 29(4), 381-389 (1985-01-01)
A HPLC method for the determination of Usal (Aspartame hydrochloride, L-aspartyl-L-phenylalanine methyl ester hydrochloride) and its decomposition products was elaborated. Aspartic acid, phenylalanine, phenylalanine methyl ester, aspartyl-phenylalanine, phenylalanyl-aspartic acid, 5-benzyl-3,6-dioxo-2-piperazineacetic acid (DOP) and Usal were separated on Separon SI C-18.
J Haginaka et al.
The Journal of pharmacy and pharmacology, 38(3), 225-226 (1986-03-01)
A sensitive, high-performance liquid chromatographic method has been developed for the determination of piperazine-2,5-dione, a new metabolite of ampicillin, in human urine. Piperazine-2,5-dione was separated from human urine on a C18-column using phosphate buffer-methanol (pH 3.5) as eluent. Subsequently, the
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