H3261
2-巯基吡啶-N-氧化物 钠盐
97.0-103.0%
别名:
2-硫代-1-氧化吡啶 钠盐, 1-羟基-2-吡啶硫酮 钠盐, 2-巯基吡啶-1-氧化物 钠盐, 吡啶硫酮 钠盐
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关于此项目
经验公式（希尔记法）:
C5H4NNaOS
化学文摘社编号:
分子量:
149.15
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
223-296-5
Beilstein/REAXYS Number:
4026050
MDL number:
产品名称
2-巯基吡啶-N-氧化物 钠盐, 97.0-103.0%
InChI
1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1
InChI key
WNGMMIYXPIAYOB-UHFFFAOYSA-M
SMILES string
[Na+].[O-][n+]1ccccc1[S-]
biological source
synthetic
assay
97.0-103.0%
color
faintly beige
white to light yellow
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
fungi
mode of action
cell membrane | interferes
Quality Level
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Application
2-巯基吡啶N-氧化物可用于与过渡金属生成双齿氧硫杂环戊烷螯合物。
2-巯基吡啶N-氧化物，也称为巯氧吡啶，可被添加到培养的细胞中，以便金属容易可不依赖于转运蛋白而进入细胞。它可用于研究微小核糖核酸病毒感染。
Biochem/physiol Actions
2-巯基吡啶N-氧化物是一种锌离子载体，可将锌转运到细胞中。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
target_organs
Nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Monitoring Apoptosis with Fluorescent Zn2+ Indicators
Eiichi Kimura, Ryoko Takasawa, et al.
Science Signaling, 2004, pl7-pl7 (2004)
Antonia A Nemec et al.
American journal of respiratory cell and molecular biology, 41(1), 69-75 (2008-12-23)
We recently reported that induction of metallothionein (MT) was critical in limiting nickel (Ni)-induced lung injury in intact mice. Nonetheless, the mechanism by which Ni induces MT expression is unclear. We hypothesized that the ability of Ni to mobilize zinc
Antiviral activity of the zinc ionophores pyrithione and hinokitiol against picornavirus infections.
B M Krenn et al.
Journal of virology, 83(1), 58-64 (2008-10-17)
We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human rhinovirus, coxsackievirus, and mengovirus multiplication. Early stages of virus infection are unaffected by these compounds. However, the cleavage of the cellular eukaryotic translation
Hui Li et al.
Small (Weinheim an der Bergstrasse, Germany), 15(28), e1901910-e1901910 (2019-06-05)
Birth control and family planning play pivotal roles in the economic growth and reduction of maternal, infant, and child mortality. Current contraceptives, such as hormonal agents and intrauterine devices, target only a small subset of reproductive processes and can have
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