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H3261

2-巯基吡啶-N-氧化物 钠盐

97.0-103.0%

别名:

2-硫代-1-氧化吡啶 钠盐, 1-羟基-2-吡啶硫酮 钠盐, 2-巯基吡啶-1-氧化物 钠盐, 吡啶硫酮 钠盐

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关于此项目

经验公式（希尔记法）:
C5H4NNaOS
化学文摘社编号:
3811-73-2
分子量:
149.15
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
24895565
EC Number:
223-296-5
Beilstein/REAXYS Number:
4026050
MDL number:
MFCD01941547
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biological source

synthetic

Quality Level

200

assay

97.0-103.0%

color

faintly beige, white to light yellow

solubility

H2O: 50 mg/mL

antibiotic activity spectrum

fungi

mode of action

cell membrane | interferes

SMILES string

[Na+].[O-][n+]1ccccc1[S-]

InChI

1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1

InChI key

WNGMMIYXPIAYOB-UHFFFAOYSA-M

Application

2-巯基吡啶N-氧化物可用于与过渡金属生成双齿氧硫杂环戊烷螯合物。
2-巯基吡啶N-氧化物，也称为巯氧吡啶，可被添加到培养的细胞中，以便金属容易可不依赖于转运蛋白而进入细胞。它可用于研究微小核糖核酸病毒感染。

Biochem/physiol Actions

2-巯基吡啶N-氧化物是一种锌离子载体，可将锌转运到细胞中。

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

target_organs

Nervous system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000543047
0000519662
0000540048
0000540048
0000543047

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Antonia A Nemec et al.
American journal of respiratory cell and molecular biology, 41(1), 69-75 (2008-12-23)
We recently reported that induction of metallothionein (MT) was critical in limiting nickel (Ni)-induced lung injury in intact mice. Nonetheless, the mechanism by which Ni induces MT expression is unclear. We hypothesized that the ability of Ni to mobilize zinc
Monitoring Apoptosis with Fluorescent Zn2+ Indicators
Eiichi Kimura, Ryoko Takasawa, et al.
Science Signaling, 2004, pl7-pl7 (2004)
B M Krenn et al.
Journal of virology, 83(1), 58-64 (2008-10-17)
We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human rhinovirus, coxsackievirus, and mengovirus multiplication. Early stages of virus infection are unaffected by these compounds. However, the cleavage of the cellular eukaryotic translation
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全球贸易项目编号

货号GTIN
H3261-100G04061833792940
H3261-1G04061826756263
H3261-10G04061833792957