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Merck
CN

I6256

Sigma-Aldrich

2-亚氨基硫烷 盐酸盐

≥98% (TLC), powder

别名:

2-亚氨基硫杂环戊烷 盐酸盐, 2-亚氨基硫烷盐酸盐 盐酸盐, 2IT, Traut 试剂

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关于此项目

经验公式（希尔记法）:
C4H7NS · HCl
化学文摘社编号:
4781-83-3
分子量:
137.63
Beilstein:
3620079
MDL编号:
MFCD00039013
UNSPSC代码:
12352100
PubChem化学物质编号:
24896086
NACRES:
NA.21

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方案

≥98% (TLC)

表单

powder

杂质

≤5% Free sulfhydryl groups

mp

198-201 °C (lit.)

溶解性

H2O: 100 mg/mL

官能团

thioether

储存温度

2-8°C

SMILES字符串

N=C1SCCC1.Cl

InChI

1S/C4H7NS.ClH/c5-4-2-1-3-6-4;/h5H,1-3H2;1H

InChI key

ATGUDZODTABURZ-UHFFFAOYSA-N

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一般描述

2-氨基硫代乙烷盐酸盐（2-IT.HCl），一种蛋白质修饰试剂，通常用于将硫醇基团连接到蛋白质和肽上。用 2-IT 修饰的毛发角蛋白纤维的拉曼光谱分析。HCl 显示出新的二硫化物基团的形成。

应用

2-硫代乙烯基盐酸盐已用于合成硫醇化 PEG（聚（乙二醇））。它可用于合成 PLA-SH（聚乙二醇-硫醇）和 PLA-PEG-SH（聚乙二醇-聚乳酸-硫醇）。
伯胺的硫醇化试剂。在 pH 7-10 下，通过脒键反应，得到游离巯基。 可用于制备二硫化物和/或硫醚连接的缀合物。

其他说明

注意：脒键具有初始伯胺的正电荷。包含五个原子的连接臂。

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000497262
0000497261
0000497260
0000497260
0000497261

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