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Merck
CN

I6256

2-亚氨基硫烷 盐酸盐

≥98% (TLC), powder

别名:

2-亚氨基硫杂环戊烷 盐酸盐, 2-亚氨基硫烷盐酸盐 盐酸盐, 2IT, Traut 试剂

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关于此项目

经验公式（希尔记法）:
C4H7NS · HCl
化学文摘社编号:
4781-83-3
分子量:
137.63
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
24896086
MDL number:
MFCD00039013
Beilstein/REAXYS Number:
3620079
Assay:
≥98% (TLC)
Form:
powder
Solubility:
H2O: 100 mg/mL

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产品名称

2-亚氨基硫烷 盐酸盐, ≥98% (TLC), powder

InChI

1S/C4H7NS.ClH/c5-4-2-1-3-6-4;/h5H,1-3H2;1H

SMILES string

N=C1SCCC1.Cl

InChI key

ATGUDZODTABURZ-UHFFFAOYSA-N

assay

≥98% (TLC)

form

powder

impurities

≤5% Free sulfhydryl groups

mp

198-201 °C (lit.)

solubility

H2O: 100 mg/mL

functional group

thioether

storage temp.

2-8°C

Quality Level

200

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General description

2-氨基硫代乙烷盐酸盐（2-IT.HCl），一种蛋白质修饰试剂，通常用于将硫醇基团连接到蛋白质和肽上。用 2-IT 修饰的毛发角蛋白纤维的拉曼光谱分析。HCl 显示出新的二硫化物基团的形成。

Other Notes

注意：脒键具有初始伯胺的正电荷。包含五个原子的连接臂。

Application

2-硫代乙烯基盐酸盐已用于合成硫醇化 PEG（聚（乙二醇））。它可用于合成 PLA-SH（聚乙二醇-硫醇）和 PLA-PEG-SH（聚乙二醇-聚乳酸-硫醇）。
伯胺的硫醇化试剂。在 pH 7-10 下，通过脒键反应，得到游离巯基。 可用于制备二硫化物和/或硫醚连接的缀合物。

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000497262
0000497261
0000497260
0000497260
0000497261

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This study aims to prepare, characterize and evaluate the pharmacokinetics of liposomal donepezil HCl (LDH) dispersed into thiolated chitosan hydrogel (TCH) in rabbits. Various hydrogels including TCH were prepared, and after characterization, TCH was selected for subsequent evaluations, due to
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