I6659
欧前胡素
≥98% (HPLC), AChE inhibitor, powder
别名:
9-[(3-METHYL-2-BUTEN-1-YL)OXY]-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
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关于此项目
经验公式（希尔记法）:
C16H14O4
化学文摘社编号:
分子量:
270.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
207-581-1
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
欧前胡素, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
off-white to light brown
solubility
DMSO: ≥5 mg/mL
storage temp.
2-8°C
SMILES string
C\C(C)=C\COc1c2OC(=O)C=Cc2cc3ccoc13
InChI
1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3
InChI key
OLOOJGVNMBJLLR-UHFFFAOYSA-N
Biochem/physiol Actions
Imperatorin is an important bioactive furanocoumarin. It is used to treat neurodegenerative diseases. It possesses anticancer, antibacterial, anti-inflammatory and HIV replication-inhibiting activities. Imperatorin serves as an inhibitor of acetylcholinesterase (AChE) and may help in treating Alzheimer′s disease (AD) and Parkinson′s disease (PD).
Imperatorin is a modulator of p38, ERK pathway.
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Features and Benefits
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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警示词
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)