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Merck
CN

I8132

scyllo-肌醇

≥98%, Myo-inositol isomer

别名:

DTLET, 青蟹肌醇

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关于此项目

经验公式(希尔记法):
C6H12O6
化学文摘社编号:
分子量:
180.16
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98%
Quality level:
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产品名称

scyllo-肌醇, ≥98%

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O

InChI key

CDAISMWEOUEBRE-CDRYSYESSA-N

InChI

1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3+,4+,5-,6-

assay

≥98%

Quality Level

Other Notes

肌醇的天然异构体。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Christophe Michon et al.
Communications biology, 3(1), 93-93 (2020-03-04)
A rare stereoisomer of inositol, scyllo-inositol, is a therapeutic agent that has shown potential efficacy in preventing Alzheimer's disease. Mycobacterium tuberculosis ino1 encoding myo-inositol-1-phosphate (MI1P) synthase (MI1PS) was introduced into Bacillus subtilis to convert glucose-6-phosphate (G6P) into MI1P. We found that
Cheryl A Hawkes et al.
The European journal of neuroscience, 31(2), 203-213 (2010-01-16)
Beta-amyloid (Abeta) peptides are thought to play a major role in the pathogenesis of Alzheimer's disease. Compounds that disrupt the kinetic pathways of Abeta aggregation may be useful in elucidating the role of oligomeric, protofibrillar and fibrillar Abeta in the
Paul H Yancey et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 133(3), 667-676 (2002-11-22)
Shallow-living marine invertebrates use free amino acids as cellular osmolytes, while most teleosts use almost no organic osmolytes. Recently we found unusual osmolyte compositions in deep-sea animals. Trimethylamine N-oxide (TMAO) increases with depth in muscles of some teleosts, skates, and
Daniela Fenili et al.
Journal of molecular medicine (Berlin, Germany), 85(6), 603-611 (2007-02-07)
Inositol is a simple polyol with eight naturally occurring stereoisomers. myo-Inositol, D-chiro- and epi-inositol have been examined as potential therapeutic agents for various diseases, with favorable results, but treatment with scyllo-inositol has not been previously investigated. Our laboratory has shown
Matthew Townsend et al.
Annals of neurology, 60(6), 668-676 (2006-12-29)
Despite progress in defining a pathogenic role for amyloid beta protein (Abeta) in Alzheimer's disease, orally bioavailable compounds that prevent its effects on hippocampal synaptic plasticity and cognitive function have not yet emerged. A particularly attractive therapeutic strategy is to

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