I8283
ICI 63,197
≥98% (HPLC)
别名:
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C9H13N5O
化学文摘社编号:
分子量:
207.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
248-383-5
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
mp
161.8-163 °C
solubility
DMSO: 13 mg/mL
storage temp.
2-8°C
SMILES string
CCCN1C(=O)C(C)=Cn2nc(N)nc12
InChI
1S/C9H13N5O/c1-3-4-13-7(15)6(2)5-14-9(13)11-8(10)12-14/h5H,3-4H2,1-2H3,(H2,10,12)
InChI key
UQDVRVNMIJAGRK-UHFFFAOYSA-N
Biochem/physiol Actions
Phosphodiesterase IV (PDE 4) inhibitor
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M D Houslay
Cellular signalling, 2(1), 85-98 (1990-01-01)
Using experimentally derived data for the activities and kinetic constants of hepatocyte cyclic AMP phosphodiesterase isoenzymes together with the derived changes in adenylate cyclase activity, due to stimulation and subsequent desensitization by glucagon, a computer model was established to simulate
J Abrahamsen et al.
Pharmacology & toxicology, 76(3), 185-189 (1995-03-01)
The possible involvement of cyclic AMP in the stimulation-evoked 3H-overflow from rabbit isolated ear artery preloaded with 3H-noradrenaline was studied. Cyclic AMP (10(-5)-3 x 10(-4)M), 8-bromo-cyclic AMP (3 x 10(-4)M) and adenosine (10(-5)-3 x 10(-4)M) enhanced stimulation-evoked 3H-overflow. Dibutyryl-cyclic AMP
Z Merican et al.
Clinical and experimental pharmacology & physiology, 10(1), 35-44 (1983-01-01)
1. Cyclic AMP and cyclic GMP levels were determined in bovine splenic nerve segments in the absence and presence of (+/-)-isoprenaline, (-)-phenylephrine, clonidine and ICI 63 197 (a phosphodiesterase inhibitor). The chosen concentrations of adrenoceptor agonists were those which are
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I8283-25MG | 04061833858547 |
| I8283-5MG | 04061832898155 |