I8754
L -异亮氨酸
≥99%
别名:
(2S,3R)-2-氨基-3-甲基戊酸, L -异异亮氨酸
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关于此项目
经验公式（希尔记法）:
C6H13NO2
化学文摘社编号:
分子量:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
216-142-3
MDL number:
Beilstein/REAXYS Number:
1721791
产品名称
L -异亮氨酸,
InChI key
AGPKZVBTJJNPAG-UHNVWZDZSA-N
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5+/m1/s1
SMILES string
CC[C@@H](C)[C@H](N)C(O)=O
assay
≥99%
form
powder
color
white to off-white
mp
285 °C
Quality Level
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Application
- 丁香假单胞菌番茄致病变种(Pseudomonas syringae pv. tomato，PSPTO4723)是DUF1330家族成员，它是生产植物毒素冠菌素的前体L-别异亮氨酸（L-allo-isoleucine）所必需的。 该研究介绍了L-别异亮氨酸在植物毒素合成中至关重要的作用，对植物病理学和生物控制策略有重大影响（Worley et al., 2013）。
Biochem/physiol Actions
异亮氨酸可用于枫糖尿病的研究。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
U Wendel et al.
Pediatric research, 25(1), 11-14 (1989-01-01)
The nonprotein amino acid L-allo-isoleucine is formed endogenously in maple syrup urine disease patients from (R)-3-methyl-2-oxo-pentanoic acid. During strict metabolic balance, the plasma L-allo-isoleucine/L-isoleucine ratio correlates inversely with the residual activity of the branched-chain 2-oxoacid dehydrogenase in fibroblasts and thus
J E Baldwin et al.
The Biochemical journal, 301 ( Pt 2), 367-372 (1994-07-15)
Potential substrates for L-delta-(alpha-aminoadipoyl)-L-(cysteinyl)-D-valine (ACV) synthetase were initially identified using both the amino-acid-dependent ATP<-->pyrophosphate exchange reaction catalysed by the enzyme and the incorporation of 14C-radiolabelled cysteine and valine into potential peptide products. S-Carboxymethylcysteine was an effective substitute for alpha-aminoadipate and
P Schadewaldt et al.
Biochemical medicine and metabolic biology, 41(2), 105-116 (1989-04-01)
Possible functional differences in the catabolism of the four branched-chain L-amino acids in maple syrup urine disease were assessed using cultured human skin fibroblast stains. Transamination and oxidative decarboxylation were comparatively studied in 90-min incubations with 1 mmole/liter of 1-14C-labeled
Chen Barazani et al.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 52, 101312-101312 (2020-03-23)
Laron Syndrome (LS), (OMIM# 262500), a rare recessively inherited disease caused by deletions or mutations of the GH receptor, gene characterized by dwarfism with low or undetectable serum IGF-I in the presence of high serum GH. In addition to dwarfism
Gian Primahana et al.
Antibiotics (Basel, Switzerland), 10(3) (2021-04-04)
The rare actinobacterium Amycolatopsis sp. strain 195334CR was found to produce previously undescribed cyclic hexapeptides, which we named amycolatomycin A and B (1 and 2). Their planar structures were determined by high-resolution mass spectrometry as well as extensive 1D and
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