L6882
D -荧光素 钠盐
luminescent, ≥98% (HPLC), lyophilized powder
别名:
( S )-2-（6-羟基-2-苯并噻唑基）-2-噻唑啉-4-羧酸 钠盐, 4,5-二氢-2-（6-羟基-2-苯并噻唑基）-4-噻唑羧酸 钠盐, 萤火虫荧光素 钠盐
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关于此项目
经验公式（希尔记法）:
C11H7N2NaO3S2
化学文摘社编号:
分子量:
302.30
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
D -荧光素 钠盐, lyophilized powder, synthetic
SMILES string
[Na+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O
InChI
1S/C11H8N2O3S2.Na/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1
InChI key
LILQLBIQROYWIA-OGFXRTJISA-M
biological source
synthetic
assay
≥98% (HPLC)
form
lyophilized powder
solubility
H2O: soluble
fluorescence
λex 328 nm; λem 532 nm in H2O
storage temp.
−20°C
Quality Level
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Application
D-萤光素钠盐用作底物，进行萤光素−荧光素酶化学发光测定，确定ATP水平。
Km 约为 2 μM 的萤火虫荧光素酶的底物。
General description
D-荧光素主要由生物发光生物体产生。 可穿过血液睾丸屏障、血脑屏障和血液胎盘屏障，进行简单循环。这种小分子对光线和氧气敏感。粉末形式的D-荧光素对水分也很敏感。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Monitoring erythrocytes in a microchip channel that narrows uniformly: Towards an improved microfluidic-based mimic of the microcirculation
Price A, et al.
Journal of Chromatography A, 1111(2), 220-227 (2006)
Real-time imaging after cerebral ischemia: model systems for visualization of inflammation and neuronal repair
Test, 506, 117-133 (2012)
Glial cell inhibition of neurons by release of ATP
Newman, Eric A
The Journal of Neuroscience, 23(5), 1659-1666 (2003)
Real-time imaging after cerebral ischemia: model systems for visualization of inflammation and neuronal repair
Methods in Enzymology, 506, 117-133 (2012)
Fabian Sesterhenn et al.
PLoS biology, 17(2), e3000164-e3000164 (2019-02-23)
Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, largely because of the failure to induce potent
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