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M1694

MPPG

≥97% (NMR), solid

别名:

(RS)-α-Methyl-4-phosphonophenylglycine

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关于此项目

经验公式（希尔记法）:
C9H12NO5P
化学文摘社编号:
169209-65-8
分子量:
245.17
NACRES:
NA.77
PubChem Substance ID:
329817701
UNSPSC Code:
12352200
MDL number:
MFCD00672651
Assay:
≥97% (NMR)
Form:
solid
Quality level:
100
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Quality Level

100

assay

≥97% (NMR)

form

solid

color

off-white

solubility

DMSO: <4 mg/mL, H2O: <4 mg/mL

SMILES string

CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O

InChI

1S/C9H12NO5P/c1-9(10,8(11)12)6-2-4-7(5-3-6)16(13,14)15/h2-5H,10H2,1H3,(H,11,12)(H2,13,14,15)

InChI key

PAONCRJPUQXPRW-UHFFFAOYSA-N

Biochem/physiol Actions

Group III/II metabotropic glutamate (mGluR) receptor antagonist.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000057413
046K4706V
046K47061
046K4706

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商品

Glutamate Receptors (G Protein Family)

Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.

T Kral et al.
Synapse (New York, N.Y.), 47(4), 278-284 (2003-01-23)
Activation of presynaptic metabotropic glutamate receptors (mGluRs) leads to a powerful inhibition of glutamate release from many synaptic terminals throughout the CNS. mGluRs as autoreceptors are believed to provide a negative feedback system that prevents potentially toxic accumulation of glutamate
Gelareh Abulwerdi et al.
Neurochemistry international, 138, 104770-104770 (2020-05-27)
Chronic dysregulated microglial activation may lead to persistent inflammation and progressive neurodegeneration. A previous study reported that ADX88178, a putative metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulator (PAM), exerts anti-inflammatory effects in microglia by activating mGluR4. We employed in
Bruce A Collings
Rapid communications in mass spectrometry : RCM, 33(10), 914-924 (2019-03-12)
Quadrupole pre-filter transmission profiles are shown to be affected by the presence of trapped ions within the pre-filter of a quadrupole mass spectrometer. Trapped ions are the result of ions reflected at the pre-filter/mass filter boundary and lead to space
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全球贸易项目编号

货号GTIN
M1694-10MG04061832091884
M1694-50MG04061832091891